Results 171 to 180 of about 116,059 (245)

Phase II study of the triple combination of rabbit ATG, ciclosporin and eltrombopag in patients with transfusion‐dependent aplastic anaemia: West Japan Hematology Study Group (W‐JHS) AA02 trial

British Journal of Haematology, EarlyView.
Summary The efficacy of a triple combination of rabbit anti‐human thymocyte immunoglobulin (rATG), ciclosporin and eltrombopag (EPAG) was prospectively evaluated in patients with severe or transfusion‐dependent non‐severe aplastic anaemia (SAA) across 29 institutions in Japan. Sixty patients were enrolled, of whom 48 had SAA. The primary end‐point, the
Fumi Nakamura, Ken Ishiyama, Ritsuro Suzuki, Hiroyuki Maruyama, Yasushi Onishi, Kensuke Usuki, Hideo Koh, Katsuto Takenaka, Ryunosuke Saiki, Seishi Ogawa, Kana Matsumoto, Takuto Takahashi, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Kenichi Yoshimura, Itaru Matsumura, Koichi Akashi, Shinji Nakao   +17 more
wiley   +1 more source

Vitamin D Deficiency in Relapsing Idiopathic Nephrotic Syndrome in Children: Prevalence, Correlates, and Therapeutic Implications. [PDF]

Int J Endocrinol
Zamani SA, Abbasi A, Bazargani B, Askarian F, Fahimi D, Moghtaderi M.   +5 more
europepmc   +1 more source

Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao, Sinan Ai, Yaoxian Wang, Yuning Liu, Jingwei Zhou, Qingqing Liu, Xu Wang, Danting Li, Xin Li, Lin Wang, Jinyi Hou, Liang Peng, Zhen Wang   +12 more
wiley   +1 more source

Ethnic and geographic disparities in proteinuria and high blood pressure: a cross-sectional study from community kidney screenings in the Washington DC area. [PDF]

BMC Nephrol
Refaey A, Bunce A, Ebeid A, Attia A, Saadi O, Abdullah I, Zarkower J, Abdou M, Callender CO, Melancon JK, Rodriguez PS.   +10 more
europepmc   +1 more source

GLOMERULOESCLEROSE SEGMENTAR E FOCAL COM FENÓTIPO DE PROTEINÚRIA NEFRÓTICA CAUSADA POR MUTAÇÃO GENÉTICA NO GENE DA PODOCINA NPHS2

M. S. Moura, Lívia Oliver Fragueiro, Barbhara Thaís Maciel Pontes, Heiner Bruggner   +3 more
openalex   +1 more source

Impact of Sequential Ramucirumab Plus Docetaxel After PD‐1 Inhibitors on Anti‐PD‐1 Antibody‐Bound T‐Cell Dynamics and Clinical Outcomes

Cancer Science, EarlyView.
Ramucirumab (RAM) plus docetaxel (DOC) after PD‐1 inhibitors showed clinical activity, with responders exhibiting maintained anti–PD‐1 (IgG4+)‐bound CD8+ T cells and decreased IgG4+ Tregs. A sequential strategy of administering RAM plus DOC during persistent anti–PD‐1 antibody binding may be beneficial in patients with advanced non‐small cell lung ...
Kinnosuke Matsumoto, Yujiro Naito, Takayuki Shiroyama, Motohiro Tamiya, Kazumi Nishino, Akihiro Tamiya, Kyoichi Okishio, Yuhei Kinehara, Tomoki Kuge, Masahide Mori, Shingo Satoh, Hidekazu Suzuki, Satoshi Tetsumoto, Toshie Niki, Yasuhiko Suga, Akio Osa, Toshiyuki Minami, Shohei Koyama, Yoshito Takeda, Nobuyuki Takakura, Atsushi Kumanogoh   +20 more
wiley   +1 more source

Prognostic impact of proteinuria in diabetic patients without chronic kidney disease undergoing percutaneous coronary intervention. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Moriya S, Iwata H, Chikata Y, Funamizu T, Doi S, Koike T, Abe K, Matsuo R, Wada H, Naito R, Ogita M, Okai I, Dohi T, Kasai T, Okazaki S, Miyauchi K, Daida H, Minamino T.   +17 more
europepmc   +1 more source

Progression of albumin/creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR) over 24 years in people with type 2 diabetes. Drivers, potential protectors and associated mortality

Diabetic Medicine, EarlyView.
Abstract Introduction The pathophysiology of chronic kidney disease (CKD) and type 2 diabetes (T2D) is multifactorial and associated with a plethora of underlying conditions and complications. Their link is reciprocal and understanding its nature, particularly over time, could improve the health of many.
Andreas Matheou, Orestis Zavlis, Steve White, Thomas McDonnell, Alexander Warner‐Levy, John Warner‐Levy, Loren Wilkins, Hellena Habte‐Asres, Abigail Lay, Liliana Shalamanova, Martin Whyte, Martin Gibson, Philip A. Kalra, Adrian Heald   +13 more
wiley   +1 more source

AVALIAÇÃO DO ÍNDICE DE CRONICIDADE EM BIÓPSIAS RENAIS DE PACIENTES COM NEFRITE LÚPICA E SUA CORRELAÇÃO COM CREATININA E PROTEINÚRIA EM 1 ANO DE ACOMPANHAMENTO

Liliana de Meira Lins Kassar, Felipe Carvalho Barros de Sousa, Vinicius Sousa da Silveira, José Guilherme Rezende Ramos Salles Gonçalves, Karoline Wayla Costa da Silva, Victoria Woronik, Luis Yu, Cristiane Bitencourt Dias, Lectícia Barbosa Jorge   +8 more
openalex   +1 more source

Literature‐informed ensemble machine learning for three‐year diabetic kidney disease risk prediction in type 2 diabetes: Development, validation, and deployment of the PSMMC NephraRisk model

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Introduction Diabetic kidney disease (DKD) and diabetic nephropathy (DN) affect around 40% of diabetic patients but lack accurate risk prediction tools that include social determinants and demographic complexity. We developed and validated an ensemble machine learning model for three‐year DKD/DN risk prediction with deployment readiness ...
Ayla M. Tourkmani, Turki J. Al‐Harbi, Ahmad Abdullah Alghamdi, Ibrahim M. Youzghadli, Faris Saad Alosaimi, Ahmed Y. Azzam   +5 more
wiley   +1 more source