Results 191 to 200 of about 116,059 (245)

Clinical Outcomes of Reduced‐Dose Cabozantinib as Third‐ or Later‐Line Therapy After Immune Checkpoint Inhibitors in Advanced Hepatocellular Carcinoma: A Real‐World Study

open access: yesHepatology Research, EarlyView.
In this real‐world post‐ICI setting, cabozantinib demonstrated meaningful clinical activity even at reduced doses, with disease control achieved in nearly half of patients. Importantly, preserved liver function (Child–Pugh class A) was the only determinant of both disease control and overall survival.
Teiji Kuzuya   +13 more
wiley   +1 more source

Impact of Early‐Line Systemic Therapies on Liver Function in Hepatocellular Carcinoma: Longitudinal Change of ALBI Score and Ammonia Level With and Without Anti‐VEGF Agents

open access: yesHepatology Research, EarlyView.
ABSTRACT Background and Aim Anti–vascular endothelial growth factor (VEGF) agents are widely used for hepatocellular carcinoma (HCC); inhibition of VEGF‐mediated liver regeneration may compromise hepatic reserve. We investigated the impact of anti‐VEGF therapy on liver function and risk factors for deterioration of albumin–bilirubin (ALBI) score during
Naoshi Nishida   +11 more
wiley   +1 more source

Avaliação de proteinúria em amostras isoladas de urina em comparação com proteinúria de 24hs

open access: green, 1996
Elvino Barros   +5 more
openalex   +1 more source

Exploring the impact of Cabotegravir‐Rilpivirine long‐acting on weight gain, body composition and quality of life in adults living with HIV

open access: yesHIV Medicine, EarlyView.
Abstract Introduction Long‐acting injectable antiretroviral therapy (ART) with Cabotegravir (CAB) and Rilpivirine (RPV) offers an alternative to daily oral regimens, improving adherence and patient satisfaction. However, its impact on body composition and metabolism remains underexplored.
Andrea De Vito   +13 more
wiley   +1 more source

Sirolimus for Secondary Prevention of Cutaneous Squamous Cell Carcinoma in Kidney Transplant Recipients: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesInternational Journal of Dermatology, EarlyView.
Meta‐analysis of randomized controlled trials shows that switching from calcineurin inhibitors (CNI) to sirolimus in kidney transplant recipients (KTRs) with prior cutaneous squamous cell carcinoma (cSCC) reduces secondary cSCC incidence but increases adverse‐event–related treatment discontinuation.
Yannick Foerster   +4 more
wiley   +1 more source

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