Results 51 to 60 of about 128,382 (221)

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

AVALIAÇÃO DA PROTEINÚRIA RENAL EM GATOS SUPLEMENTADOS COM OMEGA 3 ASSOCIADO OU NÃO AO INIBIDOR DA ENZIMA CONVERSORA DE ANGIOTENSINA. [PDF]

, 2020
A doença renal crônica (DRC) é o distúrbio renal mais frequente na clínica médica de pequenos animais. Para o estadiamento, é necessário considerar sinais clínicos, histórico médico, exames laboratoriais, estudo de imagem e patologia renal (POLZIN, 2008).
Ambrosini, Francielli, Stedille, Simone Tostes de Oliveira, Sousa, Marlos Gonçalves   +2 more
core   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Two‐Year Changes in Proteinuria and the Risk of Stroke in the Chinese Population: A Prospective Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundWhether changes in proteinuria are associated with incident stroke in the general population is unclear. This study aimed to investigate the association between changes in proteinuria and incident stroke and its subtypes. Methods and ResultsThe
Anxin Wang, Xiaoxue Liu, Zhaoping Su, Shuohua Chen, Nan Zhang, Shouling Wu, Yongjun Wang, Yilong Wang   +7 more
doaj   +1 more source

The potency of native postbiotics and paraprobiotics in modulating inflammation by affecting the gut–kidney axis

Animal Models and Experimental Medicine, EarlyView.
Native postbiotics and paraprobiotics derived from Lactobacillus and Bifidobacterium strains were administered to dextran sulfate sodium–treated C57BL/6 mice to evaluate their impact on kidney inflammation via the gut–kidney axis. Histological analysis and quantitative polymerase chain reaction of autophagy‐related genes (atg5, atg7, atg12, atg13 ...
Fatemeh Haririzadeh Jouriani, Mahnaz Torfeh, Fatemeh Ashrafian, Niloofar Rezaie, Mohsen Mohammadi, Shadi Aghamohammad, Mahdi Rohani   +6 more
wiley   +1 more source

Estudo retrospetivo de proteinúria canina quantificada pelo rácio proteína-creatinina urinário

, 2019
Dissertação de Mestrado Integrado em Medicina VeterináriaA proteinúria corresponde a uma quantidade detetável de proteínas na urina e pode surgir quando há inflamação do parênquima renal, quando as células glomerulares e/ou tubulares se encontram ...
Paz, Margarida Lemos Quintão Marques
core   +3 more sources

Protein-to-creatinine urinary in the early diagnosis of renal injury in canine pyometra

Pesquisa Veterinária Brasileira
: Kidney disease that affects bitches with pyometra may lead patients to develop chronic renal failure even after pyometra treatment. Therefore, several studies have sought to clarify the gaps in the understanding of the pathogenesis of renal injury in ...
Marcos C. Sant’Anna, Guilherme F. Martins, Karina K.M.C. Flaiban, Luiz G.C. Trautwein, Maria I.M. Martins   +4 more
doaj   +1 more source

Associação da realitividade para Ehrlichia canis em cadelas diagnosticadas com piometra e proteinúria

, 2020
Erliquiose, piometra e proteinúria são condições comuns em clínicas de pequenos animais. O o objetivo deste estudo foi avaliar a associação entre piometra e proteinúria em cadelas com reatividade a Ehrlichia canis, e para rastrear o laboratório e ultra ...
Almeida, Vivian Gomes Ferreira de
core   +1 more source

Baseline podocyte‐associated state and persistent cell–matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy

Animal Models and Experimental Medicine, EarlyView.
Two closely related BALB/c substrains exhibit different early responses to adriamycin (ADR)‐induced nephropathy. BALB/cByJcl mice showed lower baseline WT1‐positive nuclei counts and NPHS1 immunoreactivity than BALB/cAJcl mice, together with extracellular matrix and integrin programs that were enriched at baseline and persisted at Day 5.
Ryuya Nakagawa, Masaki Watanabe, Koyuki Kawamoto, Momoka Hiratsuka, Takeru Sasaki, Nobuya Sasaki   +5 more
wiley   +1 more source

Avaliação da Proteinúria no Diagnóstico e Acompanhamento de Síndrome Nefrótica [PDF]

A síndrome nefrótica (SN) é uma condição renal caracterizada pela perda excessiva de proteínas na urina, refletindo a gravidade da lesão glomerular. O presente estudo de revisão buscou fazer uma associação entre o aumento da proteinúria e a síndrome ...
Cintra, Marcos Rodrigues, Silva, Eloysa Mariane Albuquerque da   +1 more
core   +1 more source