Results 81 to 90 of about 2,229,925 (272)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Phospho‐tyrosine dependent protein–protein interaction network

Molecular Systems Biology, 2015
Post‐translational protein modifications, such as tyrosine phosphorylation, regulate protein–protein interactions (PPIs) critical for signal processing and cellular phenotypes.
Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl   +6 more
doaj   +1 more source

RocSampler: regularizing overlapping protein complexes in protein-protein interaction networks

BMC Bioinformatics, 2017
Background In recent years, protein-protein interaction (PPI) networks have been well recognized as important resources to elucidate various biological processes and cellular mechanisms.
Osamu Maruyama, Yuki Kuwahara
doaj   +1 more source

Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome [PDF]

, 2007
The severe acute respiratory syndrome coronavirus (SARS-CoV) genome is predicted to encode 14 functional open reading frames, leading to the expression of up to 30 structural and non-structural protein products.
Brunn, Albrecht von, Teepe, Carola, Caroline C Friedel, Ralph Baric, Haas, Jürgen, von Brunn, Albrecht, Simpson Jeremy C., Jeremy C. Simpson, Simpson, Jeremy C., Ralf Zimmer, Roberts, Rhonda, Carola Teepe, Rainer Pepperkok, Baric Ralph, Haas Jürgen, Simpson, Jeremy, Zimmer, Ralf, Zimmer Ralf, Caroline C. Friedel, Friedel, Caroline C., Haas, Juergen, Teepe Carola, Albrecht von Brunn, Rhonda Roberts, Jürgen Haas, Friedel Caroline C., Pepperkok Rainer, Pepperkok, Rainer, Roberts Rhonda, Baric, Ralph, Jeremy C Simpson, von Brunn Albrecht   +31 more
core   +1 more source

Protein-protein interaction network of interconnected BRD-associated hub genes.

, 2022
Protein-protein interaction network of interconnected BRD-associated hub genes.
Brandi B. Karisch (8292909), Amelia R. Woolums (8292903), Cyprianna E. Swiderski (8292906), Bindu Nanduri (21937), Andy D. Perkins (5010149), Matthew A. Scott (3915533), Abigail Finley (14053224)   +6 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Protein-protein interaction based on pairwise similarity

BMC Bioinformatics, 2009
Background Protein-protein interaction (PPI) is essential to most biological processes. Abnormal interactions may have implications in a number of neurological syndromes.
Zaki Nazar, Lazarova-Molnar Sanja, El-Hajj Wassim, Campbell Piers   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

NOXclass: prediction of protein-protein interaction types

BMC Bioinformatics, 2006
Background Structural models determined by X-ray crystallography play a central role in understanding protein-protein interactions at the molecular level.
Sommer Ingolf, Domingues Francisco S, Zhu Hongbo, Lengauer Thomas   +3 more
doaj   +1 more source

A system for the evolution of protein-protein interaction inducers

, 2021
Molecules that induce interactions between proteins, often referred to as “molecular glues”, are increasingly recognized as important therapeutic modalities and as entry points for rewiring cellular signaling networks.
Jeffrey, Dewey, Bryan, Dickinson, Saara-Anne, Azizi, Vivian, Lu   +3 more
core   +1 more source