Results 1 to 10 of about 79,704 (286)
Letter to the Editor – Oral microbiota, health and cancer: the dual face of the same coin in the field of the host-microbe interactome [PDF]
World Cancer Research Journal, 2021 Dear Editor In recent years, within the extensive research regarding human microbiota and chronic diseases, new medical and laboratory technologies have played a crucial role in understanding more complex biological pathways between human cells and ...
V. Garau +4 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2022 Despite the knowledge that mutation, multiplication, and anomalous function of α-synuclein cause progressive transformation of α-synuclein monomers into toxic amyloid fibrils in neurodegenerative diseases, the understanding of canonical signaling ...
Sharad Kumar Suthar +2 more
doaj +1 more source
Heat shock partially dissociates the overlapping modules of the yeast protein-protein interaction network: a systems level model of adaptation. [PDF]
PLoS Computational Biology, 2011 Network analysis became a powerful tool giving new insights to the understanding of cellular behavior. Heat shock, the archetype of stress responses, is a well-characterized and simple model of cellular dynamics. S.
Ágoston Mihalik, Peter Csermely
doaj +1 more source
Genomic data integration systematically biases interactome mapping. [PDF]
PLoS Computational Biology, 2018 Elucidating the complete network of protein-protein interactions, or interactome, is a fundamental goal of the post-genomic era, yet existing interactome maps are far from complete.
Michael A Skinnider +2 more
doaj +1 more source
The Hepatitis B Virus Interactome: A Comprehensive Overview
Frontiers in Microbiology, 2021 Despite the availability of a prophylactic vaccine, chronic hepatitis B (CHB) caused by the hepatitis B virus (HBV) is a major health problem affecting an estimated 292 million people globally.
Ellen Van Damme +5 more
doaj +1 more source
Tick Importin-α Is Implicated in the Interactome and Regulome of the Cofactor Subolesin
Pathogens, 2021 Ticks and tick-borne diseases (TBDs) represent a burden for human and animal health worldwide. Currently, vaccines constitute the safest and most effective approach to control ticks and TBDs.
Sara Artigas-Jerónimo +13 more
doaj +1 more source
Frontiers in Oncology, 2022 Patients who develop testicular germ cell tumours (TGCT) are at higher risk to be subfertile than the general population. The conditions are believed to originate during foetal life, however, the mechanisms behind a common aetiology of TGCT and male ...
Joshua Burton +5 more
doaj +1 more source
Antioxidants, 2021 Age-related macular degeneration (AMD) is a complex degenerative disease of the retina with multiple risk-modifying factors, including aging, genetics, and lifestyle choices.
David A. Merle +7 more
doaj +1 more source
Computational Network Inference for Bacterial Interactomics
mSystems, 2022 Since the large-scale experimental characterization of protein–protein interactions (PPIs) is not possible for all species, several computational PPI prediction methods have been developed that harness existing data from other species.
Katherine James, Jose Muñoz-Muñoz
doaj +1 more source
A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology
eLife, 2022 Neuroscience currently requires the use of antibodies to study synaptic proteins, where antibody binding is used as a correlate to define the presence, plasticity, and regulation of synapses. Gephyrin is an inhibitory synaptic scaffolding protein used to
Benjamin FN Campbell +4 more
doaj +1 more source