Results 31 to 40 of about 19,346 (166)

Chemometric Models of Differential Amino Acids at the Na_vα and Na_vβ Interface of Mammalian Sodium Channel Isoforms

Molecules, 2020
(1) Background: voltage-gated sodium channels (Navs) are integral membrane proteins that allow the sodium ion flux into the excitable cells and initiate the action potential.
Fernando Villa-Diaz, Susana Lopez-Nunez, Jordan E. Ruiz-Castelan, Eduardo Marcos Salinas-Stefanon, Thomas Scior   +4 more
doaj   +1 more source

Physiological Benefits of Dietary Lysophospholipid Supplementation in a Marine Fish Model: Deep Analyses of Modes of Action

Animals, 2023
Given the hydrophilic structure of lysophospholipids (LPLs), their dietary inclusion translates into a better emulsifying capacity of the dietary components.
Antoni Ibarz, Ignasi Sanahuja, Waldo G. Nuez-Ortín, Laura Martínez-Rubio, Laura Fernández-Alacid   +4 more
doaj   +1 more source

There is no human interactome [PDF]

Genome Biology, 2016
Protein complexes are dynamic. A new analysis of two quantitative proteomic datasets reveals cell type-specific changes in the stoichiometry of complexes, which often involve paralog switching.
openaire   +2 more sources

Curating the innate immunity interactome [PDF]

, 2010
peer-reviewedBackground: The innate immune response is the first line of defence against invading pathogens and is regulated by complex signalling and transcriptional networks.
Laird, Matthew R, Anastasia Sribnaia, Winsor, Geoffrey L., Lynn, David J, Giselle Ring, Foroushani, Amir K., Laird, Matthew R., Que, Jaimmie, Geoffrey L Winsor, Robert EW Hancock, Sribnaia, Anastasia, Hancock, Robert E.W., Ring, Giselle, Melissa Yau, Fiona SL Brinkman, Calvin Chan, Jaimmie Que, David J Lynn, Brinkman, Fiona S. L., Naseer, Misbah, Matthew R Laird, Yau, Melissa, Lo, Raymond, Raymond Lo, Chan, Calvin, Wee, Kathleen, Winsor, Geoffrey L, Breuer, Karin, Kathleen Wee, Amir K Foroushani, Hancock, R. E. W. (Robert E. W.), Brinkman, Fiona S., Misbah Naseer, Karin Breuer, Lynn, David J., Hancock, Robert E W, Foroushani, Amir K, Brinkman, Fiona S L   +37 more
core   +1 more source

Functional integrative levels in the human interactome recapitulate organ organization.

PLoS ONE, 2011
Interactome networks represent sets of possible physical interactions between proteins. They lack spatio-temporal information by construction. However, the specialized functions of the differentiated cell types which are assembled into tissues or organs ...
Ouissem Souiai, Emmanuelle Becker, Carlos Prieto, Alia Benkahla, Javier De las Rivas, Christine Brun   +5 more
doaj   +1 more source

Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance

Frontiers in Neuroanatomy, 2021
The interpeduncular nucleus (IPN) is a highly conserved limbic structure in the vertebrate brain, located in the isthmus and rhombomere 1. It is formed by various populations that migrate from different sites to the distinct domains within the IPN: the ...
Isabel M. García-Guillén, Antonia Alonso, Luis Puelles, Faustino Marín, Pilar Aroca   +4 more
doaj   +1 more source

Potential syntrophic associations in anaerobic naphthenic acids biodegrading consortia inferred with microbial interactome networks [PDF]

, 2020
Naphthenic acids (NAs) can be syntrophically metabolized by indigenous microbial communities in pristine sediments beneath oil sands tailings ponds. Syntrophy is an essential determinant of the microbial interactome, however, the interactome network in ...
Xiaofei Lv, Bin Ma, Korris Lee, Ania Ulrich
core   +1 more source

Functional Evolution of Subolesin/Akirin

Frontiers in Physiology, 2018
The Subolesin/Akirin constitutes a good model for the study of functional evolution because these proteins have been conserved throughout the metazoan and play a role in the regulation of different biological processes.
Sara Artigas-Jerónimo, Margarita Villar, Alejandro Cabezas-Cruz, James J. Valdés, James J. Valdés, James J. Valdés, Agustín Estrada-Peña, Pilar Alberdi, José de la Fuente, José de la Fuente   +9 more
doaj   +1 more source

ANIA:ANnotation and Integrated Analysis of the 14-3-3 interactome [PDF]

, 2014
The dimeric 14-3-3 proteins dock onto pairs of phosphorylated Ser and Thr residues on hundreds of proteins, and thereby regulate many events in mammalian cells.
Murugesan, Gavuthami, Mackintosh, Carol; id_orcid, Hoxhaj, Gerta, Toth, Rachel, Tinti, Michele, Madeira, Fabio   +5 more
core   +1 more source

Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry

Cell Reports, 2017
Spatiotemporal organization of protein interactions in cell signaling is a fundamental process that drives cellular functions. Given differential protein expression across tissues and developmental stages, the architecture and dynamics of signaling ...
Etienne Caron, Romain Roncagalli, Takeshi Hase, Witold E. Wolski, Meena Choi, Marisa G. Menoita, Stephane Durand, Antonio García-Blesa, Ivo Fierro-Monti, Tatjana Sajic, Moritz Heusel, Tobias Weiss, Marie Malissen, Ralph Schlapbach, Ben C. Collins, Samik Ghosh, Hiroaki Kitano, Ruedi Aebersold, Bernard Malissen, Matthias Gstaiger   +19 more
doaj   +1 more source