Results 21 to 30 of about 19,346 (166)

Schizophrenia interactome: fully-labeled interactome network [PDF]

open access: yesnpj Schizophrenia, 2016
We recently published the schizophrenia interactome1 that showed hundreds of protein-protein interactions (PPIs) of schizophrenia-associated genes, including 504 novel PPIs. Figure 2 in that article gave an overview of how many known or novel PPIs each of the schizophrenia genes had, while the specific interactions were made available through a ...
Ganapathiraju, Madhavi   +1 more
openaire   +2 more sources

A Role of the TEX101 Interactome in the Common Aetiology Behind Male Subfertility and Testicular Germ Cell Tumor

open access: yesFrontiers in Oncology, 2022
Patients who develop testicular germ cell tumours (TGCT) are at higher risk to be subfertile than the general population. The conditions are believed to originate during foetal life, however, the mechanisms behind a common aetiology of TGCT and male ...
Joshua Burton   +5 more
doaj   +1 more source

Viruses and Interactomes in Translation [PDF]

open access: yesMolecular & Cellular Proteomics, 2012
A decade of high-throughput screenings for intraviral and virus-host protein-protein interactions led to the accumulation of data and to the development of theories on laws governing interactome organization for many viruses. We present here a computational analysis of intraviral protein networks (EBV, FLUAV, HCV, HSV-1, KSHV, SARS-CoV, VACV, and VZV ...
Meyniel-Schicklin, Laurène   +3 more
openaire   +2 more sources

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells

open access: yesAntioxidants, 2021
Age-related macular degeneration (AMD) is a complex degenerative disease of the retina with multiple risk-modifying factors, including aging, genetics, and lifestyle choices.
David A. Merle   +7 more
doaj   +1 more source

The interactomics of academia

open access: yesEMBO Reports, 2023
When scientists marry each other their chances of both finding satisfactory academic jobs diminishes. What can be done to help them fulfil their potential?
openaire   +2 more sources

Computational Network Inference for Bacterial Interactomics

open access: yesmSystems, 2022
Since the large-scale experimental characterization of protein–protein interactions (PPIs) is not possible for all species, several computational PPI prediction methods have been developed that harness existing data from other species.
Katherine James, Jose Muñoz-Muñoz
doaj   +1 more source

A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology

open access: yeseLife, 2022
Neuroscience currently requires the use of antibodies to study synaptic proteins, where antibody binding is used as a correlate to define the presence, plasticity, and regulation of synapses. Gephyrin is an inhibitory synaptic scaffolding protein used to
Benjamin FN Campbell   +4 more
doaj   +1 more source

Interactome Analysis Identifies MSMEI_3879 as a Substrate of Mycolicibacterium smegmatis ClpC1

open access: yesMicrobiology Spectrum, 2023
The prevalence of drug-resistant Mycobacterium tuberculosis infections has prompted extensive efforts to exploit new drug targets in this globally important pathogen.
Emmanuel C. Ogbonna   +4 more
doaj   +1 more source

Characterization of Cystatin B Interactome in Saliva from Healthy Elderly and Alzheimer’s Disease Patients

open access: yesLife, 2023
Cystatin B is a small, multifunctional protein involved in the regulation of inflammation, innate immune response, and neuronal protection and found highly abundant in the brains of patients with Alzheimer’s disease (AD). Recently, our study demonstrated
Cristina Contini   +12 more
doaj   +1 more source

Corrigendum to: The global Microcystis interactome [PDF]

open access: yes, 2021
Corrigendum to "The global Microcystis ...
Jiang, H.   +18 more
core   +1 more source

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