Results 11 to 20 of about 79,704 (286)
Comparative interactomics [PDF]
FEBS Letters, 2005 The behavior, morphology and response to stimuli in biological systems are dictated by the interactions between their components. These interactions, as we observe them now, are therefore shaped by genetic variations and selective pressure. Similar to what has been achieved by comparing genome structures and protein sequences, we hope to obtain ...
CESARENI, GIOVANNI +5 more
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Schizophrenia interactome: fully-labeled interactome network [PDF]
npj Schizophrenia, 2016 We recently published the schizophrenia interactome1 that showed hundreds of protein-protein interactions (PPIs) of schizophrenia-associated genes, including 504 novel PPIs. Figure 2 in that article gave an overview of how many known or novel PPIs each of the schizophrenia genes had, while the specific interactions were made available through a ...
Ganapathiraju, Madhavi +1 more
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Advanced Biology, 2021 AbstractT cell activation is a fine‐tuned process that involves T cell receptor and costimulation signals. To prevent undue activation of T cells, inhibitory molecules including PD‐1 (programmed death 1) are induced and function as brakes for T cell signaling.
Qi Wang +3 more
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Interactome Analysis Identifies MSMEI_3879 as a Substrate of Mycolicibacterium smegmatis ClpC1
Microbiology Spectrum, 2023 The prevalence of drug-resistant Mycobacterium tuberculosis infections has prompted extensive efforts to exploit new drug targets in this globally important pathogen.
Emmanuel C. Ogbonna +4 more
doaj +1 more source
VDAC3 Interactomic Analysis [PDF]
Biophysical Journal, 2014 VDACs (voltage-dependent anion channel), are a small family of proteins of the mitochondrial outer membrane, considered as gatekeeper of mitochondrial metabolites and thereby controlling cross-talk between mitochondria and the rest of the cell (1-2). VDAC is also a key player in mitochondria-mediated apoptosis (3).
MESSINA, Angela Anna +6 more
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Life, 2023 Cystatin B is a small, multifunctional protein involved in the regulation of inflammation, innate immune response, and neuronal protection and found highly abundant in the brains of patients with Alzheimer’s disease (AD). Recently, our study demonstrated
Cristina Contini +12 more
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Molecules, 2020 (1) Background: voltage-gated sodium channels (Navs) are integral membrane proteins that allow the sodium ion flux into the excitable cells and initiate the action potential.
Fernando Villa-Diaz +4 more
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Animals, 2023 Given the hydrophilic structure of lysophospholipids (LPLs), their dietary inclusion translates into a better emulsifying capacity of the dietary components.
Antoni Ibarz +4 more
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Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites [PDF]
, 2011 Background information The pathology causing stages of the human malaria parasite Plasmodium falciparum reside within red blood cells that are devoid of any regulated transport system.
Bourdoncle, P. +9 more
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Functional integrative levels in the human interactome recapitulate organ organization.
PLoS ONE, 2011 Interactome networks represent sets of possible physical interactions between proteins. They lack spatio-temporal information by construction. However, the specialized functions of the differentiated cell types which are assembled into tissues or organs ...
Ouissem Souiai +5 more
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