Results 41 to 50 of about 63,382 (353)
Functional Evolution of Subolesin/Akirin
Frontiers in Physiology, 2018 The Subolesin/Akirin constitutes a good model for the study of functional evolution because these proteins have been conserved throughout the metazoan and play a role in the regulation of different biological processes.
Sara Artigas-Jerónimo +9 more
doaj +1 more source
Understanding the cellular interactome of non-alcoholic fatty liver disease
JHEP Reports, 2022 Summary Non-alcoholic fatty liver disease (NAFLD) is reaching epidemic proportions, with a global prevalence of 25% in the adult population. Non-alcoholic steatohepatitis (NASH), which can lead to cirrhosis, has become the leading indication for liver ...
S. Wallace +3 more
semanticscholar +1 more source
The Reactive Species Interactome in Red Blood Cells: Oxidants, Antioxidants, and Molecular Targets
Antioxidants, 2023 Beyond their established role as oxygen carriers, red blood cells have recently been found to contribute to systemic NO and sulfide metabolism and act as potent circulating antioxidant cells. Emerging evidence indicates that reactive species derived from
M. Cortese-Krott
semanticscholar +1 more source
ANIA:ANnotation and Integrated Analysis of the 14-3-3 interactome [PDF]
, 2014 The dimeric 14-3-3 proteins dock onto pairs of phosphorylated Ser and Thr residues on hundreds of proteins, and thereby regulate many events in mammalian cells.
Murugesan, Gavuthami +5 more
core +1 more source
A ligand-receptor interactome atlas of the zebrafish
bioRxiv, 2023 Studies in zebrafish can unravel the functions of cellular communication and thus identify novel bench-to-bedside drugs targeting cellular communication signaling molecules.
M. Chodkowski +2 more
semanticscholar +1 more source
There is no human interactome [PDF]
Genome Biology, 2016 Protein complexes are dynamic. A new analysis of two quantitative proteomic datasets reveals cell type-specific changes in the stoichiometry of complexes, which often involve paralog switching.
openaire +2 more sources
Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry
Cell Reports, 2017 Spatiotemporal organization of protein interactions in cell signaling is a fundamental process that drives cellular functions. Given differential protein expression across tissues and developmental stages, the architecture and dynamics of signaling ...
Etienne Caron +19 more
doaj +1 more source
Tau interactome and RNA binding proteins in neurodegenerative diseases
Molecular Neurodegeneration, 2022 Pathological tau aggregation is a primary neuropathological feature of many neurodegenerative diseases. Intriguingly, despite the common presence of tau aggregates in these diseases the affected brain regions, clinical symptoms, and morphology ...
Tomas Kavanagh +2 more
semanticscholar +1 more source
Frontiers in Microbiology, 2020 Nascent polypeptide-associated complex (NAC) is a ribosome-associated molecular chaperone which is present only in archaea and eukaryotes. The primary function of NAC is to shield the newly synthesized polypeptide chains from inappropriate interactions ...
Neelja Singhal +7 more
doaj +1 more source
Frontiers in Plant Science, 2021 In animals, NO is synthesized from L-arginine by three isoforms of nitric oxide synthase (NOS) enzyme. NO production and effects have also been reported in plants but the identification of its sources, especially the enzymatic ones, remains one of the ...
Pauline Chatelain +4 more
doaj +1 more source