Results 41 to 50 of about 19,346 (166)

Biophysical and Biochemical Characterization of Nascent Polypeptide-Associated Complex of Picrophilus torridus and Elucidation of Its Interacting Partners

Frontiers in Microbiology, 2020
Nascent polypeptide-associated complex (NAC) is a ribosome-associated molecular chaperone which is present only in archaea and eukaryotes. The primary function of NAC is to shield the newly synthesized polypeptide chains from inappropriate interactions ...
Neelja Singhal, Archana Sharma, Shobha Kumari, Anjali Garg, Ruchica Rai, Nirpendra Singh, Manish Kumar, Manisha Goel   +7 more
doaj   +1 more source

Identification of Partner Proteins of the Algae Klebsormidium nitens NO Synthases: Toward a Better Understanding of NO Signaling in Eukaryotic Photosynthetic Organisms

Frontiers in Plant Science, 2021
In animals, NO is synthesized from L-arginine by three isoforms of nitric oxide synthase (NOS) enzyme. NO production and effects have also been reported in plants but the identification of its sources, especially the enzymatic ones, remains one of the ...
Pauline Chatelain, Jeremy Astier, David Wendehenne, Claire Rosnoblet, Sylvain Jeandroz   +4 more
doaj   +1 more source

In-Depth Bioinformatic Study of the CLDN16 Gene and Protein: Prediction of Subcellular Localization to Mitochondria

Medicina, 2019
Background and Objectives: The defects in the CLDN16 gene are a cause of primary hypomagnesemia (FHHNC), which is characterized by massive renal magnesium wasting, resulting in nephrocalcinosis and renal failure.
Erasmia Rouka, Vassilios Liakopoulos, Konstantinos I. Gourgoulianis, Chrissi Hatzoglou, Sotirios G. Zarogiannis   +4 more
doaj   +1 more source

Interactome INSIDER: a structural interactome browser for genomic studies [PDF]

Nature Methods, 2018
We present Interactome INSIDER, a tool to link genomic variant information with structural protein-protein interactomes. Underlying this tool is the application of machine learning to predict protein interaction interfaces for 185,957 protein interactions with previously unresolved interfaces in human and seven model organisms, including the entire ...
Michael J Meyer, Juan Felipe Beltrán, Siqi Liang, Robert Fragoza, Aaron Rumack, Jin Liang, Xiaomu Wei, Haiyuan Yu   +7 more
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Motile cilia interactome data

, 2023
This data includes XL/MS and structural models for the Tetrahymena motile cilia ...
Edward M. Marcotte, Chanjae Lee, John B. Wallingford, Caitlyn L. McCafferty, Khanh Huy Bui, Ophelia Papoulas, David W. Taylor   +6 more
core   +1 more source

Overview of methods for characterization and visualization of a protein–protein interaction network in a multi-omics integration context

Frontiers in Molecular Biosciences, 2022
At the heart of the cellular machinery through the regulation of cellular functions, protein–protein interactions (PPIs) have a significant role. PPIs can be analyzed with network approaches.
Vivian Robin, Antoine Bodein, Marie-Pier Scott-Boyer, Mickaël Leclercq, Olivier Périn, Arnaud Droit   +5 more
doaj   +1 more source

BAG3 Proteomic Signature under Proteostasis Stress

Cells, 2020
The multifunctional HSP70 co-chaperone BAG3 (BCL-2-associated athanogene 3) represents a key player in the quality control of the cellular proteostasis network.
Christof Hiebel, Elisabeth Stürner, Meike Hoffmeister, Georg Tascher, Mario Schwarz, Heike Nagel, Christian Behrends, Christian Münch, Christian Behl   +8 more
doaj   +1 more source

Interactome-guided topographic maps of cancer chaperome shifts.

, 2018
A. Cancer-specific chaperome meta-interactome networks, collapsing network nodes and edges onto meta-nodes and meta-edges, highlight cancer-specific gene expression changes of chaperome functional families in context of connectivity within the high ...
Ali Hadizadeh Esfahani (4731474), Andreas A. Schuppert (4731480), Angelina Sverchkova (4731471), Julio Saez-Rodriguez (25229), Marc Brehme (4731477)   +4 more
core   +1 more source

Recent Advances in Chemical Biology Using Benzophenones and Diazirines as Radical Precursors

Molecules, 2020
The use of light-activated chemical probes to study biological interactions was first discovered in the 1960s, and has since found many applications in studying diseases and gaining deeper insight into various cellular mechanisms involving protein ...
Muhammad Murtaza Hassan, Olasunkanmi O. Olaoye   +1 more
doaj   +1 more source

Interactome modeling

FEBS Letters, 2005
A long‐term goal of the field of interactome modeling is to understand how global and local properties of complex macromolecular networks impact on observable biological properties, and how changes in such properties can lead to human diseases. The information available at this stage of development of the field provides strong evidence for the ...
openaire   +2 more sources