Results 41 to 50 of about 79,704 (286)
Recent Advances in Chemical Biology Using Benzophenones and Diazirines as Radical Precursors
Molecules, 2020 The use of light-activated chemical probes to study biological interactions was first discovered in the 1960s, and has since found many applications in studying diseases and gaining deeper insight into various cellular mechanisms involving protein ...
Muhammad Murtaza Hassan +1 more
doaj +1 more source
Classes of complex networks defined by role-to-role connectivity profiles [PDF]
, 2007 Interactions between units in phyical, biological, technological, and social systems usually give rise to intrincate networks with non-trivial structure, which critically affects the dynamics and properties of the system.
Amaral, L. A. N. +2 more
core +4 more sources
FEBS Letters, 2005 A long‐term goal of the field of interactome modeling is to understand how global and local properties of complex macromolecular networks impact on observable biological properties, and how changes in such properties can lead to human diseases. The information available at this stage of development of the field provides strong evidence for the ...
openaire +2 more sources
Biology, 2020 Mitochondria are highly dynamic and regulated organelles implicated in a variety of important functions in the cell, including energy production, fatty acid metabolism, iron homeostasis, programmed cell death, and cell signaling. Changes in mitochondrial
Loredana Moro
doaj +1 more source
SPRINT: Ultrafast protein-protein interaction prediction of the entire human interactome
, 2017 Proteins perform their functions usually by interacting with other proteins. Predicting which proteins interact is a fundamental problem. Experimental methods are slow, expensive, and have a high rate of error.
Ilie, Lucian, Li, Yiwei
core +1 more source
BcCluster: a bladder cancer database at the molecular level [PDF]
, 2016 Background: Bladder Cancer (BC) has two clearly distinct phenotypes. Non-muscle invasive BC has good prognosis and is treated with tumor resection and intravesical therapy whereas muscle invasive BC has poor prognosis and requires usually systemic ...
Bhat, Akshay +5 more
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Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers
eLife, 2017 The amyloid β peptide (Aβ) is a key player in the etiology of Alzheimer disease (AD), yet a systematic investigation of its molecular interactions has not been reported. Here we identified by quantitative mass spectrometry proteins in human brain extract
Hansen Wang +12 more
doaj +1 more source
Collagen Structure-Function Mapping Informs Applications for Regenerative Medicine
Bioengineering, 2020 Type I collagen, the predominant protein of vertebrates, assembles into fibrils that orchestrate the form and function of bone, tendon, skin, and other tissues.
James D. San Antonio +3 more
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Turkish Journal of Agriculture: Food Science and Technology, 2022 Arabidopsis thaliana has eight genes encoding members of the type P1B heavy metal–transporting ATPase, subfamily of the P-type ATPases. We focused our study on four ATPases, mainly HMA1, HMA2, HMA3, and HMA4, which are closely related and most similar in
Abdulrezzak Memon, Nuriye Meraklı
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A proteomic approach to identify endosomal cargoes controlling cancer invasiveness [PDF]
, 2017 We have previously shown that Rab17 - a small GTPase associated with epithelial polarity - is specifically suppressed by ERK2 signalling to promote an invasive phenotype.
Diaz-Vera, Jesica +8 more
core +2 more sources