Results 61 to 70 of about 63,382 (353)
Recent Advances in Chemical Biology Using Benzophenones and Diazirines as Radical Precursors
Molecules, 2020 The use of light-activated chemical probes to study biological interactions was first discovered in the 1960s, and has since found many applications in studying diseases and gaining deeper insight into various cellular mechanisms involving protein ...
Muhammad Murtaza Hassan +1 more
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Biology, 2020 Mitochondria are highly dynamic and regulated organelles implicated in a variety of important functions in the cell, including energy production, fatty acid metabolism, iron homeostasis, programmed cell death, and cell signaling. Changes in mitochondrial
Loredana Moro
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Brain cell type-specific enhancer-promoter interactome maps and disease risk association
Science, 2019 Linking enhancers to disease Enhancers are genomic regions that regulate gene expression, sometimes in a cell-dependent manner. However, most of our knowledge of human brain cell–type enhancers derives from studies of bulk human brain tissue. Nott et al.
A. Nott +25 more
semanticscholar +1 more source
Modelling the Yeast Interactome [PDF]
Scientific Reports, 2014 The topology behind biological interaction networks has been studied for over a decade. Yet, there is no definite agreement on the theoretical models which best describe protein-protein interaction (PPI) networks. Such models are critical to quantifying the significance of any empirical observation regarding those networks.
V. Janjic, R. Sharan, and N. Przulj
openaire +2 more sources
Interactome-guided topographic maps of cancer chaperome shifts.
, 2018 A. Cancer-specific chaperome meta-interactome networks, collapsing network nodes and edges onto meta-nodes and meta-edges, highlight cancer-specific gene expression changes of chaperome functional families in context of connectivity within the high ...
Ali Hadizadeh Esfahani (4731474) +4 more
core +1 more source
Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers
eLife, 2017 The amyloid β peptide (Aβ) is a key player in the etiology of Alzheimer disease (AD), yet a systematic investigation of its molecular interactions has not been reported. Here we identified by quantitative mass spectrometry proteins in human brain extract
Hansen Wang +12 more
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Collagen Structure-Function Mapping Informs Applications for Regenerative Medicine
Bioengineering, 2020 Type I collagen, the predominant protein of vertebrates, assembles into fibrils that orchestrate the form and function of bone, tendon, skin, and other tissues.
James D. San Antonio +3 more
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Turkish Journal of Agriculture: Food Science and Technology, 2022 Arabidopsis thaliana has eight genes encoding members of the type P1B heavy metal–transporting ATPase, subfamily of the P-type ATPases. We focused our study on four ATPases, mainly HMA1, HMA2, HMA3, and HMA4, which are closely related and most similar in
Abdulrezzak Memon, Nuriye Meraklı
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Nature CommunicationsDissection of the physiological interactomes of histone post-translational modifications (hPTMs) is crucial for understanding epigenetic regulatory pathways.
Yu Wang +12 more
semanticscholar +1 more source
Molecules and Cells, 2022 The envelope of Gram-negative bacteria is a vital barrier that must balance protection and nutrient uptake. Small RNAs are crucial regulators of the envelope composition and function. Here, using RIL-seq to capture the Hfq-mediated RNA-RNA interactome in
G. Matera +5 more
semanticscholar +1 more source