Results 61 to 70 of about 19,346 (166)
Diabetologia, 2005 Islet antigen-2 (IA-2), a major autoantigen in type 1 diabetes, is an enzymatically inactive member of the transmembrane protein tyrosine phosphatase (PTP) family. IA-2 is located in dense-core secretory vesicles and is involved in the regulation of insulin secretion.
Notkins, A. L. +4 more
openaire +3 more sources
Frontiers in Molecular Neuroscience, 2020 Kcc2 plays a critical role in determining the efficacy of synaptic inhibition, however, the cellular mechanisms neurons use to regulate its membrane trafficking, stability and activity are ill-defined.
Joshua L. Smalley +17 more
doaj +1 more source
The synthesis interactome (SI).
, 2018 The synthesis interactome (SI).
Octavio Martínez (184407) +1 more
core +1 more source
Fusion-positive rhabdomyosarcoma oncofusions share a common interactome
Nature CommunicationsFusion-positive rhabdomyosarcoma (FP-RMS) arises from at least seven distinct oncofusions sharing a common PAX3/7 N-terminal DNA-binding domain fused to divergent C-terminal partners. How different oncofusions produce the same cancer was unknown. Here we
S. P. Zimmerman +15 more
doaj +1 more source
The Beclin 1 interactome [PDF]
Current Opinion in Cell Biology, 2010 The mammalian ortholog of yeast Atg6/Vps30, Beclin 1, is an essential autophagy protein that has been linked to diverse biological processes, including immunity, development, tumor suppression, lifespan extension, and protection against certain cardiac and neurodegenerative diseases.
Congcong, He, Beth, Levine
openaire +2 more sources
Frontiers in Immunology, 2020 RIG-I and MDA5 are two key pattern recognition receptors that sense the invasion of RNA viruses and initiate type I interferon (IFN) response. Although these receptors are generally conserved in vertebrates, RIG-I is absent in chickens, whereas MDA5 is ...
Xian Lin +12 more
doaj +1 more source
Interactome INSIDER: a multi-scale structural interactome browser for genomic studies
, 2017 Protein interactions underlie nearly all known cellular function, making knowledge of their binding conformations paramount to understanding the physical workings of the cell.
Robert Fragoza +7 more
core +1 more source
, 2022 WARS1's interactome by mass spectrometryTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Nguyen, T (via Mendeley Data) +1 more
core +1 more source
Defining the Helicobacter pylori Disease-Specific Antigenic Repertoire
Frontiers in Microbiology, 2020 The analysis of the interaction between Helicobacter pylori (HP) and the host in vivo is an extremely informative way to enlighten the molecular mechanisms behind the persistency/latency of the bacterium as well as in the progression of the infection. An
Maria Felicia Soluri +12 more
doaj +1 more source