Results 81 to 90 of about 63,382 (353)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Short- and Long-Range RNA-RNA Interactome of SARS-CoV-2

open access: yesbioRxiv, 2020
The Coronaviridae is a family of positive-strand RNA viruses that includes SARS-CoV-2, the etiologic agent of the COVID-19 pandemic. Bearing the largest single-stranded RNA genomes in nature, coronaviruses are critically dependent on long-distance RNA ...
O. Ziv   +6 more
semanticscholar   +1 more source

VDAC3 Interactomic Analysis [PDF]

open access: yesBiophysical Journal, 2014
VDACs (voltage-dependent anion channel), are a small family of proteins of the mitochondrial outer membrane, considered as gatekeeper of mitochondrial metabolites and thereby controlling cross-talk between mitochondria and the rest of the cell (1-2). VDAC is also a key player in mitochondria-mediated apoptosis (3).
MESSINA, Angela Anna   +6 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Recent Advances in Mass Spectrometry-Based Protein Interactome Studies

open access: yesMolecular & Cellular Proteomics
The foundation of all biological processes is the network of diverse and dynamic protein interactions with other molecules in cells known as the interactome.
Shaowen Wu   +4 more
semanticscholar   +1 more source

Master Regulator Analysis of the SARS-CoV-2/Human Interactome

open access: yesbioRxiv, 2020
the recent epidemic outbreak of a novel human coronavirus called SARS-CoV-2 and causing the respiratory tract disease COVID-19 has reached worldwide resonance and a global effort is being undertaken to characterize the molecular features and evolutionary
P. Guzzi   +3 more
semanticscholar   +1 more source

A Predicted Interactome for Arabidopsis [PDF]

open access: yesPlant Physiology, 2007
Abstract The complex cellular functions of an organism frequently rely on physical interactions between proteins. A map of all protein-protein interactions, an interactome, is thus an invaluable tool. We present an interactome for Arabidopsis (Arabidopsis thaliana) predicted from interacting orthologs in yeast (Saccharomyces ...
Jane, Geisler-Lee   +5 more
openaire   +2 more sources

WARS1 interactome

open access: yes, 2022
WARS1's interactome by mass spectrometryTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Nguyen, T (via Mendeley Data)
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

open access: yesNature Communications, 2022
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy.
P. Havugimana   +7 more
semanticscholar   +1 more source

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