Results 81 to 90 of about 53,983 (298)
Chemistry & Biology, 2008 MacBeath and colleagues (Kaushansky et al., 2008) use a protein array technology to find binding partners of ErbB4 in a genome-wide and quantitative fashion, shedding new light on how ErbB4 initiates cellular signaling events and why ErbB4 is not a potent oncogene.
Takahashi, Terry T., Li, Shuwei
openaire +2 more sources
Advanced Science, EarlyView.In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen +8 more
wiley +1 more source
Network Medicine in the Age of Biomedical Big Data
Frontiers in Genetics, 2019 Network medicine is an emerging area of research dealing with molecular and genetic interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale biomedical data generation offers a unique opportunity to assess the effect and
Abhijeet R. Sonawane +8 more
doaj +1 more source
The Mammalian Septin Interactome [PDF]
Frontiers in Cell and Developmental Biology, 2017 Septins are GTP-binding and membrane-interacting proteins with a highly conserved domain structure involved in various cellular processes, including cytoskeleton organization, cytokinesis, and membrane dynamics. To date, 13 different septin genes have been identified in mammals (SEPT1 to SEPT12 and SEPT14), which can be classified into four distinct ...
Neubauer, Katharina, Zieger, Barbara
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MiGiNull/Ece1p-interactome: v1.0
<p>Network and Functional Analysis of Ece1p-Human Interactome for Novel Target Identification</p ...
MiGiNull
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Estimated interactome coverages and interactome sizes.
, 2012 We report the means and standard deviations for the reciprocal hits data over all the -value thresholds that we investigate. These results assume that the S. cerevisiae interactome is complete at interactions.
Charlotte M. Deane (50371) +3 more
core +1 more source
Advanced Science, EarlyView.In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong +13 more
wiley +1 more source
ligand-discovery/interactome-signatures: Publication release
Interactome signature modeling for the Ligand Discovery ...
Miquel Duran-Frigola
core +1 more source
The synthesis interactome (SI).
, 2018 The synthesis interactome (SI).
Octavio Martínez (184407) +1 more
core +1 more source
Advanced Science, EarlyView.Our findings establish SUMOylation as a key post‐translational control layer in auxin signaling. We show that SIZ1‐mediated SUMOylation of LBD29 promotes its association with ARF7, stabilizing a transcriptional hub that governs lateral root development.
Jiaxuan Sui +7 more
wiley +1 more source