Results 71 to 80 of about 53,983 (298)
Defining the Helicobacter pylori Disease-Specific Antigenic Repertoire
Frontiers in Microbiology, 2020 The analysis of the interaction between Helicobacter pylori (HP) and the host in vivo is an extremely informative way to enlighten the molecular mechanisms behind the persistency/latency of the bacterium as well as in the progression of the infection. An
Maria Felicia Soluri +12 more
doaj +1 more source
Quantum Genetics and Quantum Automata Models of Quantum-Molecular Evolution Involved in the Evolution of Organisms and Species [PDF]
, 2012 Previous theoretical or general approaches to the problems of Quantum Genetics and Molecular Evolution are considered in this article from the point of view of Quantum Automata Theory first published by the author in 1971 and further developed in several
I. C. Baianu
core
p300 interactome transcription factors.
, 2013 Transcription factors in the p300 interactome which demonstrated significant regulation during A404 differentiation vs.
Philip S. Tsao (110770) +2 more
core +1 more source
The Beclin 1 interactome [PDF]
Current Opinion in Cell Biology, 2010 The mammalian ortholog of yeast Atg6/Vps30, Beclin 1, is an essential autophagy protein that has been linked to diverse biological processes, including immunity, development, tumor suppression, lifespan extension, and protection against certain cardiac and neurodegenerative diseases.
Congcong, He, Beth, Levine
openaire +2 more sources
Advanced Science, EarlyView.ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang +7 more
wiley +1 more source
Native Nanodiscs and the Convergence of Lipidomics, Metabolomics, Interactomics and Proteomics
Applied Sciences, 2019 The omics disciplines remain largely distinct sciences due to the necessity of separating molecular classes for different assays. For example, water-soluble and lipid bilayer-bound proteins and metabolites are usually studied separately.
Michael Overduin, Mansoore Esmaili
doaj +1 more source
TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes
Advanced Science, EarlyView.In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang +11 more
wiley +1 more source
Advanced Science, EarlyView.A previously unrecognized microprotein, MP104, encoded by ZEB1‐AS1, emerges as a critical driver of colorectal cancer progression. MP104 links ubiquitin‐mediated protein degradation with translational reprogramming via the UBE2O–AMPKα2–mTOR–EIF4B axis, revealing an unrecognized layer of oncogenic regulation.
Fang Chen +14 more
wiley +1 more source
International Journal of Plant BiologyAquaporins are transmembrane proteins that mediate the transport of water, as well as various ions and molecules. In plants, they play a critical role in numerous processes, including stress adaptation, nutrition, cellular communication, and ...
Alvaro Lopez-Zaplana
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 Mutations in PARK2 gene are the most frequent cause of familial forms of Parkinson’s disease (PD). This gene encodes Parkin, an E3 ubiquitin ligase involved in several cellular mechanisms, including mitophagy.
Mara Zilocchi +12 more
doaj +1 more source