Results 121 to 130 of about 761,097 (212)

PIRT-Seq: a high-resolution whole-genome assay to identify protein-coding genes. [PDF]

Nucleic Acids Res
Goodall ECA, Hodges F, Kok W, Permana B, Cuddihy T, Yang Z, Kahler N, Shires K, Pullela K, Torres VVL, Rooke JL, Delhaye A, Collet JF, Bryant JA, Forde BM, Hemm MR, Henderson IR.   +16 more
europepmc   +1 more source

Knowing when to stop: Transcription termination on protein-coding genes by eukaryotic RNAPII. [PDF]

Mol Cell, 2023
Rodríguez-Molina JB, West S, Passmore LA.   +2 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Correction: RNA editing events and expression profiles of mitochondrial protein-coding genes in the endemic and endangered medicinal plant, <i>Corydalis saxicola</i>. [PDF]

Front Plant Sci
Li C, Liu H, Qin M, Tan YJ, Ou XL, Chen XY, Wei Y, Zhang ZJ, Lei M.   +8 more
europepmc   +1 more source

Evolution under a model of functionally buffered deleterious mutations can lead to positive selection in protein-coding genes. [PDF]

Evolution, 2023
Shen R, Wenzel M, Messer PW, Aquadro CF.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Annotation of protein-coding genes in 49 diatom genomes from the Bacillariophyta clade. [PDF]

Sci Data
Nenasheva N, Pitzschel C, Webster CN, Hart AJ, Wegrzyn JL, Bengtsson MM, Hoff KJ.   +6 more
europepmc   +1 more source

ChIPBase v3.0: the encyclopedia of transcriptional regulations of non-coding RNAs and protein-coding genes. [PDF]

Nucleic Acids Res, 2023
Huang J, Zheng W, Zhang P, Lin Q, Chen Z, Xuan J, Liu C, Wu D, Huang Q, Zheng L, Liu S, Zhou K, Qu L, Li B, Yang J.   +14 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

AlphaMissenseR: an integrated framework for investigating missense mutations in human protein-coding genes. [PDF]

Bioinform Adv
Nguyen TN, Lee T, Turaga N, Gentleman R, Geistlinger L, Morgan M.   +5 more
europepmc   +1 more source