Results 141 to 150 of about 11,665,453 (372)
mAbsCharge heterogeneity is one of the commonly monitored quality attributes in biotherapeutics. It can impact the stability, efficacy, and safety of products, but it can also affect the pharmacokinetics, binding affinity, and overall biological activity of ...
Gangadhar Dhulipala +4 more
doaj +1 more source
Protein-protein diffusional encounter
Biophysical Journal, 1997 Protein-protein association is clearly a very important process in biology, including events such as signal transduction, immune response, and transcription. Protein-protein association rates are in the range of 103 to 109 M-l S-1, with those in the diffusion-limited regime having rates of .106 M-1 s.
openaire +3 more sources
The non-protein nitrogen of extracts of Pisum sativum [PDF]
, 1954 Sheenah K. Bisset
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Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
Protein-Protein Interactions [PDF]
Revista Brasileira de Ciências Farmacêuticas, 2004 Graziella Pedrazzi, Igor Stagljar
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STRING v9.1: protein-protein interaction networks, with increased coverage and integration
Nucleic Acids Res., 2012 Complete knowledge of all direct and indirect interactions between proteins in a given cell would represent an important milestone towards a comprehensive description of cellular mechanisms and functions. Although this goal is still elusive, considerable
Andrea Franceschini +10 more
semanticscholar +1 more source
CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS [PDF]
, 1934 Walther F. Goebel +2 more
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Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Protein Hypernetworks: a Logic Framework for Interaction Dependencies and Perturbation Effects in Protein Networks [PDF]
arXiv, 2011 Motivation: Protein interactions are fundamental building blocks of biochemical reaction systems underlying cellular functions. The complexity and functionality of such systems emerge not from the protein interactions themselves but from the dependencies between these interactions.
arxiv
The proteins of Hevea brasiliensis latex. 2. Isolation of the α-globulin of fresh latex serum [PDF]
, 1955 B. L. Archer, E. G. Cockbain
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