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Integrating analysis of multi-omics summary data identifies novel plasma protein biomarkers and drug targets for bladder cancer. [PDF]
Discov OncolCao J +7 more
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HPOseq: a deep ensemble model for predicting the protein-phenotype relationships based on protein sequences. [PDF]
BMC BioinformaticsZhao K +6 more
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PDGF-BB promotes oral submucosal fibrosis by driving phenotypic transformation and autophagy in oral mucosal fibroblasts through downregulation of circHIPK3. [PDF]
Sci RepZhang H +5 more
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Protein-derived cofactors: chemical innovations expanding enzyme catalysis.
Chem Soc RevGraciano A, Liu A.
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Biochemical Society Transactions, 2010
In the present article, we describe the two standard high-throughput methods for identification of protein complexes: two-hybrid screens and TAP (tandem affinity purification) tagging. These methods have been used to characterize the interactome of Saccharomyces cerevisiae, showing that the majority of proteins are part of complexes, and that complexes
Williamson, Mike P. +1 more
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In the present article, we describe the two standard high-throughput methods for identification of protein complexes: two-hybrid screens and TAP (tandem affinity purification) tagging. These methods have been used to characterize the interactome of Saccharomyces cerevisiae, showing that the majority of proteins are part of complexes, and that complexes
Williamson, Mike P. +1 more
openaire +4 more sources
Analysis of Protein-Protein Interactions by Protein Microarrays
2021The analysis of the proteome and the interactome would be useful for a better understanding of the pathophysiology of several disorders, allowing the identification of potential specific markers for early diagnosis and prognosis, as well as potential targets of intervention.
Rodrigo Barderas, Ana Montero-Calle
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Protein myristoylation in protein–lipid and protein–protein interactions
Biophysical Chemistry, 1999Various proteins in signal transduction pathways are myristoylated. Although this modification is often essential for the proper functioning of the modified protein, the mechanism by which the modification exerts its effects is still largely unknown. Here we discuss the roles played by protein myristoylation, in both protein-lipid and protein-protein ...
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