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Prediction of protein aggregation
The scientific community is very interested in protein aggregation because of its involvement in several neurodegenerative diseases and its significance in industry. Remarkably, fibrillar aggregates are utilized naturally for constructing structural scaffolds or creating biological switches and may be intentionally designed to construct versatile ...Kavyan, Khalili +3 more
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Protein aggregation and neurodegenerative disease
Nature Medicine, 2004C. Ross, Michelle A. Poirier
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2020
The study of protein aggregates has a long history. While in the first decades until the 80ies of the 20th century only the observation of the presence of such aggregates was reported, later the biochemistry of the formation and the biological effects of theses aggregates were described.
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The study of protein aggregates has a long history. While in the first decades until the 80ies of the 20th century only the observation of the presence of such aggregates was reported, later the biochemistry of the formation and the biological effects of theses aggregates were described.
openaire +1 more source
The role of biomolecular condensates in protein aggregation
Nature Reviews ChemistryBrent S. Visser +2 more
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In Vitro Cellular & Developmental Biology - Animal, 1996
J, Prachar, K, Hlubinova, A, Feldsamova
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J, Prachar, K, Hlubinova, A, Feldsamova
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Mechanisms, regulation and functions of the unfolded protein response
Nature Reviews Molecular Cell Biology, 2020Claudio Hetz +2 more
exaly
Molecular mechanisms of protein aggregation from global fitting of kinetic models
Nature Protocols, 2016G. Meisl +7 more
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The mechanisms of integral membrane protein biogenesis
Nature Reviews Molecular Cell Biology, 2021Ramanujan Shankar Hegde, Robert J Keenan
exaly