Results 121 to 130 of about 8,850,756 (327)

Structure-Based Function Prediction of Functionally Unannotated Structures in the PDB: Prediction of ATP, GTP, Sialic Acid, Retinoic Acid and Heme-bound and -Unbound (Free) Nitric Oxide Protein Binding Sites [PDF]

open access: yesarXiv, 2015
Due to increased activity in high-throughput structural genomics efforts around the globe, there has been an accumulation of experimental protein 3D structures lacking functional annotation, thus creating a need for structure-based protein function assignment methods.
arxiv  

Investigations in Serum Copper. I. Nature of Serum Copper and its Relation to the Iron-Binding Protein in Human Serum. [PDF]

open access: bronze, 1947
Carl Holmberg   +4 more
openalex   +1 more source

BeAtMuSiC: prediction of changes in protein–protein binding affinity on mutations

open access: yesNucleic Acids Res., 2013
The ability of proteins to establish highly selective interactions with a variety of (macro)molecular partners is a crucial prerequisite to the realization of their biological functions.
Y. Dehouck   +3 more
semanticscholar   +1 more source

Editorial: Women in pharmacology of infectious diseases: 2021

open access: yesFrontiers in Pharmacology, 2022
Elena K. Schneider-Futschik   +2 more
doaj   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

How does a protein reach its binding locus: sliding along DNA chain or not? [PDF]

open access: yesarXiv, 2016
In gene expression, various kinds of proteins need to bind to specific locus of DNA. It is still not clear how these proteins find their target locus. In this study, the mean first-passage time (FPT) of protein binding to its target locus on DNA chain is discussed by a chain-space coupled model.
arxiv  

Protein Binding of β-Lactam Antibiotics in Critically Ill Patients: Can We Successfully Predict Unbound Concentrations?

open access: yesAntimicrobial Agents and Chemotherapy, 2013
The use of therapeutic drug monitoring (TDM) to optimize beta-lactam dosing in critically ill patients is growing in popularity, although there are limited data describing the potential impact of altered protein binding on achievement of target ...
G. Wong   +6 more
semanticscholar   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

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