Results 151 to 160 of about 10,846,120 (403)

Molecular Processes Studied at a Single-Molecule Level Using DNA Origami Nanostructures and Atomic Force Microscopy

Molecules, 2014
DNA origami nanostructures allow for the arrangement of different functionalities such as proteins, specific DNA structures, nanoparticles, and various chemical modifications with unprecedented precision.
Ilko Bald, Adrian Keller
doaj   +1 more source

THYROXINE-BINDING BY SERUM PROTEIN IN PREGNANCY AND IN THE NEWBORN [PDF]

, 1958
Jacob Robbins, James H. Nelson
openalex   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

PPI-hotspotID for detecting protein–protein interaction hot spots from the free protein structure

eLife
Experimental detection of residues critical for protein–protein interactions (PPI) is a time-consuming, costly, and labor-intensive process. Hence, high-throughput PPI-hot spot prediction methods have been developed, but they have been validated using ...
Yao Chi Chen, Karen Sargsyan, Jon D Wright, Yu-Hsien Chen, Yi-Shuian Huang, Carmay Lim   +5 more
doaj   +1 more source

AZORUBIN-BINDING CAPACITY AND PROTEIN COMPOSITION OF SERUM OF RATS SUBJECTED TO TOURNIQUET SHOCK AND TO TREATMENT WITH CARBON TETRACHLORIDE [PDF]

, 1952
Ulrich Westphal, Robert DeArmond, Stanley G. Priest, John F. Stets   +3 more
openalex   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

The Demonstration of the Iron-binding Globulin (Transferrin) in Serum and Urine Proteins by Use of 59Fe Combined with Paper Electrophoresis [PDF]

, 1955
F. C. Neale
openalex   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Investigations in Serum Copper. I. Nature of Serum Copper and its Relation to the Iron-Binding Protein in Human Serum. [PDF]

, 1947
Carl Holmberg, C.‐B. Laurell, Åke Åkeson, Annikki Linnasalmi, Pentti Laukkanen   +4 more
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source