Results 241 to 250 of about 4,013,382 (355)

Identification of fibrinogen as a plasma protein binding partner for lecanemab biosimilar IgG. [PDF]

Ann Clin Transl Neurol
Bellier JP, Román Viera AM, Christiano C, Anzai JAU, Moreno S, Campbell EC, Godwin L, Li A, Chen AY, Alam SM, Saba A, Yoo HB, Yang HS, Chhatwal JP, Selkoe DJ, Liu L.   +15 more
europepmc   +1 more source

In Vitro Analyses of the Binding of 131I-Iodide to Milk Protein

, 1968
G. D. Potter, David R. McIntyre
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Generating and validating renewable affimer protein binding reagents targeting SH2 domains. [PDF]

Sci Rep
Heseltine SJ, Billenness GJ, Martin HL, Tiede C, Tang AAS, Foy E, Reddy G, Gibson N, Johnson M, Webb ME, McPherson MJ, Tomlinson DC.   +11 more
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Non-linear plasma protein binding of cannabidiol. [PDF]

J Cannabis Res
Babayeva M, Srdanovic I.
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Structures of complete HIV-1 TAR RNA portray a dynamic platform poised for protein binding and structural remodeling. [PDF]

Nat Commun
Bou-Nader C, Link KA, Suddala KC, Knutson JR, Zhang J.   +4 more
europepmc   +1 more source

Purification and Properties of a Leucine-binding Protein from Escherichia coli

, 1968
W.R. Penrose, George E. Nichoalds, Jeanette R. Piperno, Dale L. Oxender   +3 more
openalex   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source