Results 241 to 250 of about 4,079,288 (357)

Protein Binding of Semisynthetic Penicillins

, 1964
Edward Quinn
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Identification of potential human targets for epigallocatechin gallate through a novel protein binding site screening approach. [PDF]

J Mol Model
Hirci J, Škufca S, Kunej T, Janežič D, Konc J.   +4 more
europepmc   +1 more source

Protein Bindings. I. Binding of 2-(4'-Hydroxyphenylazo) benzoic Acid to Bovine Serum Albumin

, 1968
IKUO MORIGUCHI, Sakae Wada, Hajime Sano
openalex   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Improved Prediction of Ligand-Protein Binding Affinities by Meta-modeling. [PDF]

J Chem Inf Model
Lee HJ, Emani PS, Gerstein MB.
europepmc   +1 more source

The tumor–microbe connection

Molecular Oncology, EarlyView.
Tumor‐associated bacteria (TAB) dynamically influence cancer biology by modulating tumor progression, metastatic spread, and therapeutic efficacy. Their presence redefines the tumor microenvironment (TME) as a microbial–host interface, yet mechanistic insights remain limited. Understanding TAB colonization routes, functional impacts, and crosstalk with
Gerlanda Vella, Maria Rescigno
wiley   +1 more source

N-Terminal Protein Binding and Disorder-to-Order Transition by a Synthetic Receptor. [PDF]

Biochemistry
Mockler NM, Ramberg KO, Flood RJ, Crowley PB.   +3 more
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Photophysical Properties and Protein Binding Studies of Piperazine-Substituted Anthracene-BODIPY Dyads for Antimicrobial Photodynamic Therapy. [PDF]

Molecules
O'Sullivan S, Tabrizi L, Turzańska K, Clark IP, Fitzgerald-Hughes D, Pryce MT.   +5 more
europepmc   +1 more source