Results 271 to 280 of about 10,846,120 (403)

PRODIGY: a web server for predicting the binding affinity of protein-protein complexes

open access: yesBioinform., 2016
L. Xue   +4 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Protein Binding Site Representation in Latent Space. [PDF]

open access: yesMol Inform
Lohmann F   +5 more
europepmc   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

Estimating Absolute Protein-Protein Binding Free Energies by a Super Learner Model. [PDF]

open access: yesJ Chem Inf Model
Chaves EJF   +7 more
europepmc   +1 more source

The RNA Binding Protein Quaking Regulates Formation of circRNAs

open access: yesCell, 2015
S. Conn   +9 more
semanticscholar   +1 more source

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