Results 281 to 290 of about 10,846,120 (403)

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

Nature, 1990
Andrew H. Sinclair, P. Berta, Mark S. Palmer, J. Ross Hawkins, Beatrice L. Griffiths, Matthijs J. Smith, J. W. Foster, A. Frischauf, R. Lovell-Badge, Peter N. Goodfellow   +9 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Characterization of nuclease stability and poly(A)-binding protein binding activity of chemically modified poly(A) tail for <i>in vivo</i> applications. [PDF]

RSC Chem Biol
Hashimoto A, Kunitomo Y, Kikuchi I, Yamada H, Kobayashi K, Soshiroda K, Aman H, Kimura Y, Yamamoto J, Shiraishi Y, Uchida S, Abe H, Iwai H.   +12 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Correction: DiffBP: generative diffusion of 3D molecules for target protein binding. [PDF]

Chem Sci
Lin H, Huang Y, Zhang O, Ma S, Liu M, Li X, Wu L, Ji S, Hou T, Li SZ.   +9 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Computational design of an improved photoswitchable psychedelic based on light absorption, membrane permeation and protein binding.

Phys Chem Chem Phys
Palmisano VF, Agnorelli C, Faraji S, Nogueira JJ.   +3 more
europepmc   +1 more source

Naturally Occurring Angiotensin Peptides Enhance the SARS-CoV-2 Spike Protein Binding to Its Receptors. [PDF]

Int J Mol Sci
Oliveira KX, Bablu FE, Gonzales ES, Izumi T, Suzuki YJ.   +4 more
europepmc   +1 more source

Effects of Dietary Niacin Concentration and Protein Content on Gastric Acidity and Vitamin B₁₂ Binding Capacity of Gastric Mucosa in Rats

, 1968
Tatsuo Koyanagi, Shoji Yamada
openalex   +2 more sources