Results 151 to 160 of about 3,693,345 (304)

Biochemical studies on plant glycerol-3- phosphate acyltransferase [PDF]

, 2003
sn-Glycerol-3-phosphate acyltransferase [G3PAT, PlsB (E.coli), EC 2.3.1.15] is an enzyme involved in glycerolipid biosynthesis, catalysing the acylation of glycerol-3-phosphate (G3P) to produce lysophosphatidic acid (LPA). Chilling tolerance in plants is
Hayman, Matthew William
core  

Homology modeling of 3D structure of human chitinase-like protein CHI3L2

Open Life Sciences, 2010
Iershov Anton, Odynets Konstantin, Kornelyuk Alexander, Kavsan Vadim   +3 more
doaj   +1 more source

SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis. [PDF]

Cancer Res, 2022
Loevenich LP, Tschurtschenthaler M, Rokavec M, Silva MG, Jesinghaus M, Kirchner T, Klauschen F, Saur D, Neumann J, Hermeking H, Jung P.   +10 more
europepmc   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

Advanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha, Ashwani Kumar Gupta, Nate Schmidt, Richard M. Green, John G. Purdy, Jason A. Wertheim   +5 more
wiley   +1 more source

Coordinated improvement of maize grain yield and protein quality by the ZmMADS8-ZmMADS47-O2 module and a G protein gamma subunit

Crop Journal
Improving protein quality and grain yield traits coordinately is an important goal for crop breeding. To date, many protein-quality or grain-yield regulation genes have been identified.
Yunfu Li, Qiang Ning, Ran Zhao, Dan Liu, Nan Li, Qing Xiong, Qin Sun, Yanfang Du, Ruijie Mao, Jimin Zhan, Zuxin Zhang, Lei Liu   +11 more
doaj   +1 more source

Red blood cell proteomics reveal remnant protein biosynthesis and folding pathways in PIEZO1-related hereditary xerocytosis. [PDF]

Front Physiol, 2022
Caulier A, Jankovsky N, Gautier EF, El Nemer W, Guitton C, Ouled-Haddou H, Guillonneau F, Mayeux P, Salnot V, Bruce J, Picard V, Garçon L.   +11 more
europepmc   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

NECAB family of neuronal calcium-binding proteins in health and disease

Neural Regeneration Research
The N-terminal EF-hand calcium-binding proteins 1–3 (NECAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one EF-hand calcium-binding domain and a functionally less well characterized C-terminal ...
Diones Bueno, Michael K.E. Schäfer, Sudena Wang, Michael J. Schmeisser, Axel Methner   +4 more
doaj   +1 more source

SERTAD1 Sensitizes Breast Cancer Cells to Doxorubicin and Promotes Lysosomal Protein Biosynthesis. [PDF]

Biomedicines, 2022
Nguyen HA, Vu SH, Jung S, Lee BS, Nguyen TNQ, Lee H, Lee HG, Myagmarjav D, Jo T, Choi Y, Lee MS.   +10 more
europepmc   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source