Unravelling the roles of two senescent enhanced MYB transcription factors in the regulation of anthocyanin biosynthesis in Arabidopsis thaliana [PDF]
MYB90 and MYB75 are two MYB transcription factors that regulate anthocyanin biosynthesis in Arabidopsis. Prior to this study a microarray experiment indicated that MYB90 was required for senescence associated anthocyanin biosynthesis.
Warner, Nichola Maxine
core
A Lipoate-Protein Ligase Is Required for De Novo Lipoyl-Protein Biosynthesis in the Hyperthermophilic Archaeon Thermococcus kodakarensis. [PDF]
Appl Environ Microbiol, 2022 Jin JQ, Sato T, Hachisuka SI, Atomi H.
europepmc +1 more source
Advanced Science, EarlyView.Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang +11 more
wiley +1 more source
Structural Studies Reveal the Role of Helix 68 in the Elongation Step of Protein Biosynthesis. [PDF]
mBio, 2022 Cimicata G +11 more
europepmc +1 more source
Advanced Science, EarlyView.Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu +10 more
wiley +1 more source
Rescue of Glycosylphosphatidylinositol-Anchored Protein Biosynthesis Using Synthetic Glycosylphosphatidylinositol Oligosaccharides. [PDF]
ACS Chem Biol, 2021 Guerrero PA +5 more
europepmc +1 more source
Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer
Advanced Science, EarlyView.The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu +13 more
wiley +1 more source
Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions
Advanced Science, EarlyView.Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han +11 more
wiley +1 more source
Plant sterol metabolism with emphasis on glycoalkaloid biosynthesis in potato [PDF]
, 2007 Glycoalkaloids are secondary metabolites present within species of the family Solanaceae. They are toxic to humans and animals, and it is important to keep the levels in potato (Solanum tuberosum L.) tubers below the safe limit for consumption ...
Arnqvist, Lisa
core
Down-regulation of the bacterial protein biosynthesis machinery in response to weeks, years, and decades of soil warming. [PDF]
Sci Adv, 2022 Söllinger A +11 more
europepmc +1 more source