Results 81 to 90 of about 3,693,345 (304)

Foxg1 and companions: Not only transcription factors

Neural Regeneration Research
Moving from the most recent results on Foxg1 biology, we first summarize the available information on some special pleiotropic effectors of neurodevelopmental interest, involved in controlling both transcription and post-transcriptional steps of gene ...
Antonello Mallamaci, Osvaldo Artimagnella, Gabriele Liuzzi   +2 more
doaj   +1 more source

Turnip mosaic virus P1 suppresses JA biosynthesis by degrading cpSRP54 that delivers AOCs onto the thylakoid membrane to facilitate viral infection.

PLoS Pathogens, 2021
Jasmonic acid (JA) is a crucial hormone in plant antiviral immunity. Increasing evidence shows that viruses counter this host immune response by interfering with JA biosynthesis and signaling.
Mengfei Ji, Jinping Zhao, Kelei Han, Weijun Cui, Xinyang Wu, Binghua Chen, Yuwen Lu, Jiejun Peng, Hongying Zheng, Shaofei Rao, Guanwei Wu, Jianping Chen, Fei Yan   +12 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Diversity and Evolution of the Phenazine Biosynthesis Pathway [PDF]

, 2010
Phenazines are versatile secondary metabolites of bacterial origin that function in biological control of plant pathogens and contribute to the ecological fitness and pathogenicity of the producing strains.
Blankenfeldt, Wulf, Thomashow, L., Weller, David M, Lemanceau, P., Mazurier, Sylvie, S., Mazurier, S., Raaijmakers, J., Mavrodi, Dmitri V. Mavrodi, Heide, L., Peever, Tobin L., Raaijmakers, Jos M., Mavrodi, Dmitri V., Parejko, J., Thomashow, Linda S., Peever, T., Thomashow, L.S., Mazurier, Sylvie, Mavrodi, D., Mavrodi, Olga V., Mavrodi, D.V., Blankenfeldt, W., Weller, David M., Parejko, James A, Thomashow, Linda S, Mavrodi, O.V., Peever, Tobin L, Raaijmakers, J.M., Lemanceau, Philippe, Weller, D., Weller, D.M., Heide, Lutz, Mavrodi, O., Lemanceau, Philippe, P., Parejko, James A., Mavrodi, Olga V, Parejko, J.A., Peever, T.L., Raaijmakers, Jos M, Mavrodi, Dmitri V   +38 more
core   +1 more source

Comparative Proteomic Analysis Reveals Proteins Putatively Involved in Toxin Biosynthesis in the Marine Dinoflagellate Alexandrium catenella

Marine Drugs, 2013
Alexandrium is a neurotoxin-producing dinoflagellate genus resulting in paralytic shellfish poisonings around the world. However, little is known about the toxin biosynthesis mechanism in Alexandrium. This study compared protein profiles of A.
Da-Zhi Wang, Yue Gao, Lin Lin, Hua-Sheng Hong   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Primary structure and glycosylation of the S-layer protein of Haloferax volcanii [PDF]

, 1990
The outer surface of the archaebacterium Haloferax volcanii (formerly named Halobacterium volcanii) is covered with a hexagonally packed surface (S) layer. The gene coding for the S-layer protein was cloned and sequenced.
Sumper, Manfred, Mengele, R., Berg, E., Strobel, I.   +3 more
core   +1 more source

Studies and application of the enzymes of fluorometabolite biosynthesis in Streptomyces cattleya [PDF]

, 2010
This thesis focuses on studies investigating the structure of intermediates involved in fluorometabolite biosynthesis, and the potential applications of the fluorinase enzyme in positron emission tomography (PET). Chapter 1 introduces the rare natural
Onega, Mayca
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Alternative Haem Biosynthesis Pathway: Structure, Function and Properties of Sirohaem Decarboxylase [PDF]

, 2014
Haem, a cyclic tetrapyrrole, is found in organisms from all three domains of life. Haem is a prosthetic group for many proteins involved in essential biological processes such as respiration and oxygen transport.
Palmer, David James
core