Results 251 to 260 of about 1,141,379 (303)
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Protein C and S Deficiency

Seminars in Thrombosis and Hemostasis, 1999
Protein C and S deficiency states predispose affected individuals to thrombosis, especially venous thrombosis of the lower extremities, usually beginning in the teenage years. Treatment of these patients is generally with oral anticoagulation, following initial heparinization.
F A, Nizzi, H S, Kaplan
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Pregnancy and protein C deficiency

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1992
This report examines a patient with recurrent attacks of thrombo-embolism due to a protein C deficiency. Alterations in the coagulation during pregnancy and the possible consequences of an altered coagulation during pregnancy will be discussed.
A M, van Heusden   +2 more
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Severe homozygous protein C deficiency

The Journal of Pediatrics, 1984
An infant with recurrent purpura fulminans in the first year of life was found to have severe homozygous deficiency of protein C (less than 1% of normal levels). The episodes of purpura fulminans were controlled by infusions of fresh frozen plasma containing protein C.
R H, Sills   +4 more
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Homozygous protein C deficiency—management with protein C concentrate

European Journal of Pediatrics, 1995
Two unrelated female infants with homozygous protein C (Pr C) deficiency are reported. Both are of U.K. Pakistani origin and in each case the parents are consanguinous. A previous sibling had died in each family. Both sets of parents were shown to be carriers. The concentration of Pr C in both infants was low at birth.
V, Baliga   +5 more
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Anesthetic Implications of Protein C Deficiency

Anesthesia & Analgesia, 1986
Chez un nourrisson de 3,5 mois deficit congenital en proteine C plusieurs anesthesies endotracheales sont realisees sans complications.
R C, Wetzel   +3 more
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Protein C Deficiency

Journal of the American Podiatric Medical Association, 2005
We describe the management of a patient who presented to a family-practice clinic with gangrenous digits. After a thorough evaluation, she was found to have protein C deficiency, which produced a hypercoagulable state. Differential diagnosis in the evaluation of the coagulopathic patient with appropriate hematologic tests is briefly discussed.
Travis A, Motley, Clint L, Vanlandingham
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Hereditary protein C deficiency during pregnancy

American Journal of Obstetrics and Gynecology, 1987
Hereditary protein C, a primary hypercoagulable state, has not been previously associated with preeclamptic toxemia. A woman with previous preeclamptic toxemia and fetal deaths presented with recurrent deep vein thrombosis during her third pregnancy.
B, Brenner   +4 more
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Severe antigenic deficiency of protein C associated with moderate deficiency of protein C activity

Thrombosis Research, 1985
The available literature shows that activated protein C is a potent anticoagulant enzyme in vitro (1,2). Moderate deficiency of protein C (30-60X of normal levels) of an hereditary type has been shown recently to be associated with recurrent thrombotic disease (3,4).
E, Melissari   +3 more
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Protein C Deficiency

Archives of Surgery, 1988
Familial hypercoagulable states are a collection of syndromes characterized by an inherited deficiency of various proteins involved in the control of coagulation and include antithrombin III, plasminogen, protein C, and protein S. Affected patients usually develop venous thrombosis as adults. During a 15-month interval, we identified five patients with
D F, Tollefson   +4 more
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Heterozygous protein C deficiency presenting as severe protein C deficiency and peripartum thrombosis: Successful treatment with protein C concentrate

Obstetrics & Gynecology, 1995
Complications of pregnancy, including thrombosis and increased fetal loss, have been described in women with heterozygous protein C deficiency.We report an unusual case of umbilical cord thrombosis, acute renal failure, and cutaneous venous thrombosis associated with severe protein C deficiency in the heterozygous infant of a normal mother.
T M, Goodwin, G, Gazit, E M, Gordon
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