Results 1 to 10 of about 1,237 (113)
In 1977, three years after the discovery of the γ-carboxy glutamic acid,[1][1] Richard DiScipio reported on the identification of a new vitamin K-dependent protein which was named protein S.[2][2] Three years later, Frederick Walker reported that bovine protein S functioned as a cofactor ...
Armando D’Angelo +1 more
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Sabine Kroiss, Manuela AlbisettiDivision of Hematology, University Children’s Hospital, Zurich, SwitzerlandAbstract: Protein C is one of the major inhibitors of the coagulation system that downregulate thrombin generation.
Sabine Kroiss, Manuela Albisetti
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Purpura Fulminans in a 20-Year-Old Female
A previously healthy 20-year-old female presented with extensive retiform purpura located at the face, upper and lower limbs, one week after an episode of acute tonsillitis.
Francisca Alves +2 more
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Genetic Variants in the Protein S (PROS1) Gene and Protein S Deficiency in a Danish Population
Protein S (PS) deficiency is a risk factor for venous thromboembolism (VTE) and can be caused by variants of the gene encoding PS (PROS1). This study aimed to evaluate the clinical value of molecular analysis of the PROS1 gene in PS-deficient ...
Ole Halfdan Larsen +3 more
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Protein S Deficiency with Favourable Foetomaternal Outcome: A Case Report [PDF]
Protein S is a multifunctional plasma protein, whose deficiency,results in a rare congenital thrombophilia, inherited in an autosomal dominant pattern.
Swati Sugandha +3 more
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Deep Vein Thrombosis in Protein S Deficiency
Protein S is a vitamin K-dependent anticoagulant protein. It functions as a cofactor of activated protein C to inactivate activated factor V (FVa) and activated factor VIII (FVIIIa). Its deficiency is a rare condition and can lead to deep vein thrombosis,
A Joshi, J P Jaiswal
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A Difficult Case in Clinical Practice: Combined Polycythaemia Vera and Protein S Deficiency in a Patient with both Thrombotic and Bleeding Complications [PDF]
Polycythemia Vera (PV) is a chronic myeloproliferative disorder which is characterised by a high risk of developing arterial as well as venous thromboembolic complications like deep vein thrombosis, stroke, cortical vein thrombosis and rarely acute ...
Sushanth Wattal +4 more
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Vascular access thrombosis is one of the major causes of morbidity in patients maintained on chronic hemodialysis. Thrombophilia has been recognized as a risk factor of vascular access thrombosis.
Eun Jin Cho +7 more
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Protein S Deficiency: A Case Report
Protein S is a glycoprotein created by the body that aids in the prevention of a hypercoagulable state. Protein S-deficient patients are placed on anticoagulant regimens, as there is no current definitive cure. Failure to bring balance to the hematological system in these patients will lead to complications such as widespread clot formation and ...
Gandhi, Shirley M +2 more
openaire +2 more sources
Background Protein S, which circulates in plasma in both free and bound forms, is an anticoagulant protein that stimulates activated protein C and tissue factor pathway inhibitor.
Elisabetta Castoldi +8 more
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