Results 41 to 50 of about 15,453 (247)

INHERITED PROTEIN C AND PROTEIN S DEFICIENCY IN RENAL TRANSPLANT CANDIDATES OF SINDH PROVINCE, PAKISTAN

open access: yesGomal Journal of Medical Sciences, 2019
Background: Thrombophilia is a common risk factor for venous thromboembolism. The objective of this study was to determine prevalence of inherited protein C and protein S deficiency in renal transplant candidates of Sindh Province, Pakistan. Material &
Muhammad Hanif Mengal   +3 more
doaj   +1 more source

Carrier frequencies of antithrombin, protein C, and protein S deficiency variants estimated using a public database and expression experiments

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Background Genetic deficiencies of antithrombin (AT), protein C (PC), and protein S (PS) are risk factors for venous thromboembolism. In the general population, the prevalence of heterozygous deficiency of AT, PC, and PS are reported as approximately 0 ...
Keiko Maruyama, Koichi Kokame
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Protein S Deficiency with Recurrent Deep Vein Thrombosis and Post Thrombotic Syndrome: A Case Report

open access: yesJournal of Nepal Medical Association, 2022
Protein S is a vitamin K-dependent protein that acts as a break in secondary hemostasis by inactivating activated factor V and activated factor VIII. We report a case of a 40 years old male who had the first episode of deep vein thrombosis of the left ...
Shashank Neupane   +5 more
doaj   +1 more source

Three new Alpha1-Antitrypsin deficiency variants help to define a C-Terminal region regulating conformational change and polymerization

open access: yes, 2012
Alpha1-antitrypsin (AAT) deficiency is a hereditary disorder associated with reduced AAT plasma levels, predisposing adults to pulmonary emphysema.
Fra Anna M.   +76 more
core   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Myocardial infarction in a pregnant woman revealing a transitional deficit in protein S: a rare case report

open access: yesThe Pan African Medical Journal, 2019
The occurrence of myocardial ischemia and myocardial infarction in pregnancy is relatively rare, the occurrence of myocardial infarction in pregnancy is associated with cardiovascular risk factors.
Souleymane Diakite   +3 more
doaj   +1 more source

Protein C or Protein S deficiency associates with paradoxically impaired platelet‐dependent thrombus and fibrin formation under flow

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2022
Background Low plasma levels of protein C or protein S are associated with venous thromboembolism rather than myocardial infarction. The high coagulant activity in patients with thrombophilia with a (familial) defect in protein C or S is explained by ...
Sanne L. N. Brouns   +12 more
doaj   +1 more source

Unveiling Procoagulant States in Acute Pulmonary Embolism: A Case Series and Insights [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Venous Thromboembolism (VTE) is a common yet potentially life-threatening condition. The most frequent presentations of venous thrombosis are Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE).
Padamati Advytha Reddy   +4 more
doaj   +1 more source

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