Results 41 to 50 of about 24,775,971 (291)

Preventative management against thromboembolism using fresh frozen plasma in a coronary artery bypass graft patient with protein S deficiency: a case report

JA Clinical Reports, 2018
Protein S deficiency patient is characterized by recurrent thrombosis, and its risk is higher intraoperatively, especially in cardiac surgery involving cardiopulmonary bypass. Two heparin cessation periods are defined in cardiac surgery.
Kenzaburou Sugimoto, Mamoru Kadosaki, Atsushi Egawa, Rina Tokitou, Miho Urayama, Mamoru Takeuchi   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Inherited Thrombophilia and the Risk of Arterial Ischemic Stroke: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Inherited thrombophilias are well‐established predisposing factors for venous thromboembolism, but their role in arterial thrombosis, such as arterial ischemic stroke, remains uncertain.
Thita Chiasakul, Elizabeth De Jesus, Jiayi Tong, Yong Chen, Mark Crowther, David Garcia, Chatree Chai‐Adisaksopha, Steven R. Messé, Adam Cuker   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Apixaban Use in Patients with Protein C and S Deficiency: A Case Series and Review of Literature

Journal of Blood Medicine, 2022
Khalid Al Sulaiman,1– 4 Faisal Alsuwayyid,2 Abdulrahman Alrashidi,2 Mohammed Alhijris,2 Faisal Almutairi,2 Fahad Alharthi,2 Laila Carolina Abu Esba,1– 3 Ohoud Aljuhani,4,5 Hisham A Badreldin1– 3 1Pharmaceutical Care Department, King Abdulaziz Medical ...
Al Sulaiman K, Alsuwayyid F, Alrashidi A, Alhijris M, Almutairi F, Alharthi F, Abu Esba LC, Aljuhani O, Badreldin HA   +8 more
doaj  

Unveiling Procoagulant States in Acute Pulmonary Embolism: A Case Series and Insights [PDF]

Journal of Clinical and Diagnostic Research
Venous Thromboembolism (VTE) is a common yet potentially life-threatening condition. The most frequent presentations of venous thrombosis are Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE).
Padamati Advytha Reddy, S Gokula Krishnan, N Nalini Jayanthi, S Pugazhendhi, S Nagarjun   +4 more
doaj   +1 more source

Carrier frequencies of antithrombin, protein C, and protein S deficiency variants estimated using a public database and expression experiments

Research and Practice in Thrombosis and Haemostasis, 2021
Background Genetic deficiencies of antithrombin (AT), protein C (PC), and protein S (PS) are risk factors for venous thromboembolism. In the general population, the prevalence of heterozygous deficiency of AT, PC, and PS are reported as approximately 0 ...
Keiko Maruyama, Koichi Kokame
doaj   +1 more source

Protein S Deficiency and The Mechanism of Protein S in Hemostasis and Atherosclerosis [PDF]

, 2023
Protein S (PS) is Vitamin K dependant protein which plays a role in regulating the blood clotting process in the body. Protein S deficiency is explained as a condition characterized by reduced levels of protein S in the serum so that it makes the blood ...
Rizki, Dira Kurnia, Ramadhan, Ananda Karunia, Agistany, Nur Feby Febiana, Akhyar, Raditya Bayu Farizil, Hunaifi, Ilsa   +4 more
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Myocardial infarction in a pregnant woman revealing a transitional deficit in protein S: a rare case report

The Pan African Medical Journal, 2019
The occurrence of myocardial ischemia and myocardial infarction in pregnancy is relatively rare, the occurrence of myocardial infarction in pregnancy is associated with cardiovascular risk factors.
Souleymane Diakite, Fatima Zohra Radi, Jamila Zarzur, Mohamed Cherti   +3 more
doaj   +1 more source