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Laboratory Diagnosis of Protein C Deficiency

Seminars in Thrombosis and Hemostasis, 1990
No assays presently available test all aspects of protein C function.
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Heterozygous protein C deficiency type I

Blut, 1989
Protein C is a vitamin K-dependent plasma protein which has anticoagulatory and profibrinolytic properties as a result of inactivating coagulation factors Va and VIIIa and enhancing fibrinolysis. Heterozygous protein C deficiency is well known to be a risk factor for thromboembolic diseases. We here present a family with 16 members deficient in protein
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Clinical management of protein C deficiency

Expert Opinion on Pharmacotherapy, 2001
Protein C (PC) is a vitamin K-dependent plasma protein that is structurally similar to other coagulation factors such as prothrombin and Factor X. PC is converted to its active anticoagulant form by a thrombin-thrombomodulin complex on the surface of capillary endothelial cells.
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Anticoagulant Blood Factor Deficiencies (Protein C)

2007
Anti-coagulant proteins are essential to maintain blood hemostatis for the supply of oxygen and nutrients to tissue cells and for the removal of toxic by-products from metabolism. Hereditary or acquired deficiencies of Protein C, Protein S, or Antithrombin III can lead to disease states such as deep vein thrombosis (DVT) with the possibility of ...
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Endothelium-Dependent Protein C Activation in Hereditary Protein C Deficiency

Thrombosis and Haemostasis
AbstractProtein C (PC) activation on endothelial cells is a critical antithrombotic mechanism. Hereditary PC deficiency (PCD), which is caused by mutations in the PROC gene, can predispose affected individuals to thrombophilia. Previous studies investigated activated protein C (APC) generation in PCD patients without including endothelial cells, which ...
Nadine Schwarz   +7 more
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Protein C and S Deficiencies

2018
This chapter discusses the pathophysiology, inheritance, and epidemiology of protein C and protein S deficiencies. The chapter discusses the impact of protein C and protein S deficiencies on pregnant women and details suggested medical and anesthetic management of affected individuals.
James P. R. Brown, Joanne Douglas
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Protein C and protein S deficiencies.

Seminars in hematology, 1997
The protein C (PC) pathway, with its cofactor protein S (PS), is an important natural antithrombotic mechanism. Both PC and PS deficiencies have been implicated in thrombophilia. The molecular basis for hereditary PC and PS deficiencies is highly heterogeneous, with a large spectrum of mutations that have various effects on the expression of the ...
M, Aiach   +5 more
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The contemporary management of cancers of the sinonasal tract in adults

Ca-A Cancer Journal for Clinicians, 2023
Rajat Thawani
exaly  

Protein C Deficiency in Austria

Seminars in Thrombosis and Hemostasis, 1985
I, Pabinger-Fasching, E, Deutsch
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Protein S Deficiency

2009
Markus Braun-Falco   +199 more
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