Results 191 to 200 of about 715,907 (344)

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Conformational Rearrangement in C-Reactive Protein Is Required for Proinflammatory Actions on Human Endothelial Cells [PDF]

, 2004
Tarek Khreiss, Levente József, Lawrence A. Potempa, János G. Filep   +3 more
openalex   +1 more source

Vitamin A Emulsion Encapsulated with Whey Protein Isolate-Soybean Lecithin Enhances Surimi Gel Structure and Protein Conformation. [PDF]

Foods
Chen M, Huang X, Lin Y, Yi S.
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Acetylation of Human TCF4 (TCF7L2) Proteins Attenuates Inhibition by the HBP1 Repressor and Induces a Conformational Change in the TCF4::DNA Complex

, 2013
Susanne Elfert, Andreas Weise, Katja Bruser, Martin L. Biniossek, Sabine Jägle, Niklas Senghaas, Andreas Hecht   +6 more
openalex   +2 more sources

Peer Review #3 of "GISA: using Gauss Integrals to identify rare conformations in protein structures (v0.1)"

, 2020
Christian Grønbæk, Thomas Hamelryck, Peter Røgen   +2 more
openalex   +1 more source

The Heat-Induced Gel-Sol Transition in Coated Tofu: A Study on Protein Conformation and Microstructural Changes. [PDF]

Gels
Xie X, Li M, Diao X, Sun S, Wen M, Zhou X, Zhao L, Li Y, Lv P, Li B, Shen X, Huang Z, Chen H, Zhang K.   +13 more
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Ultrasound-driven modulation of myofibrillar protein conformation promotes salt uptake and taste enhancement in marinated chicken breast. [PDF]

Food Chem X
Li H, Chen F, Li H, Yan X, Yu Q, Sun C, Wen R.   +6 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source