Results 191 to 200 of about 734,673 (317)

On the conformation of proteins: Hydrophobic ordering of strands in β-pleated sheets

, 1977
Michael J.E. Sternberg, Janet M. Thornton   +1 more
openalex   +1 more source

Allosteric behavior irrespective of conformational change of enzyme protein. Sigmoidal concentration dependence of rate of action of saccharifying α‐amylase on maltose [PDF]

, 1976
Haruko Fujimori, Masatake Ohnishi, Mitsuaki Sakoda, Ryuichi Matsuno, Keitaro Hiromi   +4 more
openalex   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

The Heat-Induced Gel-Sol Transition in Coated Tofu: A Study on Protein Conformation and Microstructural Changes. [PDF]

Gels
Xie X, Li M, Diao X, Sun S, Wen M, Zhou X, Zhao L, Li Y, Lv P, Li B, Shen X, Huang Z, Chen H, Zhang K.   +13 more
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Protein Conformation [PDF]

core   +1 more source

Cross-linking studies on the conformation and dimerization of myelin basic protein in solution.

, 1978
E.E. Golds, Pascal Braun
openalex   +1 more source

Influence of local interactions on protein structure. I. Conformational energy studies of N‐acetyl‐N′‐methylamides of pro‐X and X‐pro dipeptides [PDF]

, 1977
S. Scott Zimmerman, Harold A. Scheraga
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Investigation of Co-Assembly of Peanut Protein and Rice Protein: Effects on Protein Conformation and Immunoglobulin E Binding Capacity. [PDF]

Foods
Geng Q, McClements DJ, Dai T, Li C, Wu Z, Chen H.   +5 more
europepmc   +1 more source