Results 221 to 230 of about 6,634,608 (387)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Investigation of Co-Assembly of Peanut Protein and Rice Protein: Effects on Protein Conformation and Immunoglobulin E Binding Capacity. [PDF]

Foods
Geng Q, McClements DJ, Dai T, Li C, Wu Z, Chen H.   +5 more
europepmc   +1 more source

Sequence homology based protein-protein interacting residue predictions and the applications in ranking docked conformations

, 2012
Li C. Xue
openalex   +2 more sources

The Magnitude of the Light-induced Conformational Change in Different Rhodopsins Correlates with Their Ability to Activate G Proteins [PDF]

, 2009
Hisao Tsukamoto, David Farrens, Mitsumasa Koyanagi, Akihisa Terakita   +3 more
openalex   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Chemoenzymatic synthesis of sialylated and fucosylated mucin analogs reveals glycan-dependent effects on protein conformation and degradation. [PDF]

RSC Chem Biol
Wood AM, Wardzala CL, Kramer JR.
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Empowering AlphaFold2 for protein conformation selective drug discovery with AlphaFold2-RAVE. [PDF]

Elife
Gu X, Aranganathan A, Tiwary P.
europepmc   +1 more source

Ligand-induced conformational switch in an artificial bidomain protein scaffold [PDF]

, 2019
Corentin Léger, Thibault Di Méo, Magali Aumont‐Nicaise, Christophe Velours, D. Durand, I. Li de la Sierra-Gallay, Herman van Tilbeurgh, Niko Hildebrandt, Michel Desmadril, Agathe Urvoas, Marie Valerio‐Lepiniec, Philippe Minard   +11 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source