Results 241 to 250 of about 734,673 (317)

Cloning, expression and enzyme activity delineation of two novel CANT1 mutations: the disappearance of dimerization may indicate the change of protein conformation and even function. [PDF]

Orphanet J Rare Dis, 2020
Wang HD, Guo LJ, Feng ZQ, Zhang DW, Zhang MT, Gao Y, Chen CL, Zhu BF.   +7 more
europepmc   +1 more source

CONFORMATIONAL CHANGES IN HEME PROTEINS AND MODEL COMPOUNDS

, 1976
K. Spartalian, Georgina Lang
openalex   +2 more sources

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

N-acetyl cysteine: A tool to perturb SARS-CoV-2 spike protein conformation

, 2021
Debnath U, Mitra A, Dewaker V, Prabhakar YS, Tadala R, Krishnan K, Wagh P, Velusamy U, Subramani C, Agarwal S, Vrati S, Baliyan A, Kurpad AV, Bhattacharyya P, Mandal A.   +14 more
europepmc   +1 more source

Compound Heterozygous MRPS14 Variants Associated With Leigh Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT MRPS14 (uS14m) is a nuclear‐encoded ribosomal protein important for mitochondria‐specific translation. To date, only a single individual with a recessive MRPS14‐related disorder (also known as COXPD38) has been reported. We report an additional subject possessing novel compound heterozygous MRPS14 variants (p.Asp37Asn, p.Asn60Asp). The subject
Maria Gabriela Otero, Christina Freeman, Ruchi Shah, Renkui Bai, Hong Cui, Marian Castro, Zachary Myers, Eric Choy, Derek Chan, Molly Easter, Sophia Y. Zhao, Madeline Babros, Ruchi Garg, Matthew Deardorff, Franklin Moser, Tyler Mark Pierson   +15 more
wiley   +1 more source

Effect of Protein Conformation and AMP Protonation State on Fireflies' Bioluminescent Emission. [PDF]

Molecules, 2019
Garcia-Iriepa C, Navizet I.
europepmc   +1 more source

Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Elucidating dysfunctional connectivity patterns among key brain regions in Huntington's disease (HD) underlying progression may have implications for developing treatment and therapeutic evaluation. Objective Explore the relationship between abnormal spontaneous resting‐state activity and atrophy in HD‐specific brain regions and ...
Yinghua Jing, Imis Dogan, Rena Theda Overbeck, Kathrin Reetz, Sandro Romanzetti   +4 more
wiley   +1 more source

Conformational changes and functional properties of acid-modified soy protein.

, 1985
Naotoshi Matsudomi, Tetsuyuki Sasaki, Akio Kato, Kunihiko Kobayashi   +3 more
openalex   +2 more sources

Hyperoxia Induced Alteration of Chromatin Structure in Human Bone Marrow Derived Primary Mesenchymal Stromal Cells

Advanced Biology, EarlyView.
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe, Samantha Kaonis, Natalie Calahan, Neda Kabi, Soham Ghosh   +4 more
wiley   +1 more source

Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition.

, 1985
Ian A. Wilson, Danielh . Haft, E.D. Getzoff, John A. Tainer, Richard A. Lerner, Sydney Brenner   +5 more
openalex   +1 more source