Results 251 to 260 of about 734,673 (317)

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Role of protein conformation and weak interactions on γ-gliadin liquid-liquid phase separation. [PDF]

Sci Rep, 2019
Sahli L, Renard D, Solé-Jamault V, Giuliani A, Boire A.   +4 more
europepmc   +1 more source

Chaperoning mitochondrial biogenesis [PDF]

, 1994
Langer, Thomas, Morimoto, Richard I., Neupert, Walter   +2 more
core  

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Molecular insight into the therapeutic potential of phytoconstituents targeting protein conformation and their expression. [PDF]

Phytomedicine, 2019
Tiwari V.
europepmc   +1 more source

Effects of Escherichia coli secB mutations on pre-maltose binding protein conformation and export kinetics.

, 1988
Carol A. Kumamoto, P M Gannon
openalex   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability. [PDF]

Nucleic Acids Res, 2018
Rodrigues CH, Pires DE, Ascher DB.
europepmc   +1 more source

Monoclonal antibodies as probes of conformational changes in protein-engineered cytochrome c.

, 1988
James F. Collawn, C J A Wallace, Amanda E. I. Proudfoot, Yvonne Paterson   +3 more
openalex   +1 more source