Results 311 to 320 of about 6,634,608 (387)

The Effect of Modified Starches on the Gel Properties and Protein Conformation of Nemipterus virgatus Surimi.

Journal of texture studies, 2019
The study investigated the effect of native cassava starch (NCS), hydroxypropylated starch (HS), acetic acid esterification starch (AAES), acetylated distarch phosphate (ADPS) on gel properties and protein conformation of Nemipterus virgatus surimi ...
Hongbo Mi, Cong Wang, Qing Su, Xuepeng Li, Shumin Yi, Jianrong Li   +5 more
semanticscholar   +1 more source

Conformation spaces of proteins

Proteins: Structure, Function, and Bioinformatics, 2001
We report a simple method for measuring the accessible conformational space explored by an ensemble of protein structures. The method is useful for diverse ensembles derived from molecular dynamics trajectories, molecular modeling, and molecular structure determinations. It can be used to examine a wide range of time scales.
D C, Sullivan, I D, Kuntz
openaire   +2 more sources

Control of Protein Conformation and Orientation on Graphene.

Journal of the American Chemical Society, 2019
Graphene-based biosensors have attracted considerable attention due to their advantages of label-free detection and high sensitivity. Many such biosensors utilize noncovalent Van der Waals force to attach proteins onto graphene surface while preserving ...
Shuai Wei, Xingquan Zou, Jiayi Tian, Hao Huang, Wen Guo, Zhan Chen   +5 more
semanticscholar   +1 more source

Protein conformational prediction

Trends in Biochemical Sciences, 1989
The prediction of the secondary and tertiary structure of globular and membrane proteins is reviewed. Prospects are encouraging for future developments, but present algorithms require cautious interpretation.
openaire   +2 more sources

Protein Conformation Generation via Force-Guided SE(3) Diffusion Models

International Conference on Machine Learning
The conformational landscape of proteins is crucial to understanding their functionality in complex biological processes. Traditional physics-based computational methods, such as molecular dynamics (MD) simulations, suffer from rare event sampling and ...
Yan Wang, Lihao Wang, Yuning Shen, Yiqun Wang, Huizhuo Yuan, Yue Wu, Quanquan Gu   +6 more
semanticscholar   +1 more source

Structure Language Models for Protein Conformation Generation

International Conference on Learning Representations
Proteins adopt multiple structural conformations to perform their diverse biological functions, and understanding these conformations is crucial for advancing drug discovery.
Jiarui Lu, Xiaoyin Chen, Stephen Zhewen Lu, Chence Shi, Hongyu Guo, Y. Bengio, Jian Tang   +6 more
semanticscholar   +1 more source

Exploring Protein Conformational Diversity

2018
The native state of proteins is composed of conformers in dynamical equilibrium. In this chapter, different issues related to conformational diversity are explored using a curated and experimentally based database called CoDNaS (Conformational Diversity in the Native State).
Monzon, Alexander Miguel, Fornasari, Maria Silvina, Zea, Diego Javier, Parisi, Gustavo Daniel   +3 more
openaire   +3 more sources

Lethal protein conformations

Trends in Biochemical Sciences, 1980
A discussion of how snake venom neurotoxins may imitate the structures of arrow poisons and chemical transmitters in order to paralyse and ...
M.J. Dufton, R.C. Hider
openaire   +1 more source

Conformational stability of globular proteins

Trends in Biochemical Sciences, 1990
The conformational stability of ribonuclease T1 has been measured as a function of the variables of most interest to biochemists: temperature, pH, salt concentration, disulfide-bond content and amino acid sequence. The results provide insight into the forces that stabilize globular proteins.
openaire   +2 more sources

Conformation Polymorphism of Polyglutamine Proteins

Trends in Biochemical Sciences, 2018
Expanded polyglutamine (polyQ) stretches within endogenous proteins cause at least nine human diseases. The structural basis of polyQ pathogenesis is the key to understanding fundamental mechanisms of these diseases, but it remains unclear and controversial due to a lack of polyQ protein structures at the single-atom level. Various hypotheses have been
Xinran Feng, Shouqing Luo, Boxun Lu
openaire   +2 more sources