Results 91 to 100 of about 3,146,871 (312)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Sentinel 2-Based Nitrogen VRT Fertilization in Wheat: Comparison between Traditional and Simple Precision Practices

Agronomy, 2019
This study aimed to compare standard and precision nitrogen (N) fertilization with variable rate technology (VRT) in winter wheat (Triticum aestivum L.) by combining data of NDVI (Normalized Difference Vegetation Index) from the Sentinel 2 satellite ...
Marco Vizzari, Francesco Santaga, Paolo Benincasa   +2 more
doaj   +1 more source

The Diversity of Seed Size and Nutrient Content of Lablab Bean from Three Locations in Indonesia [PDF]

, 2019
Lablab bean (Dolichos lablab L.) is one of the legume species that have the potential as an alternative food source for Indonesian people. The purpose of this study was to examine the diversity of seed size and nutritional content of six lablab bean ...
Fauzi, Ahmad, Prihanta, Wahyu, Purwanti, Elly   +2 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Effect of Organic and Inorganic Fertilization on Yield and Quality Traits of Tritordeum, ‘Bulel’ Variety under Dry Conditions in Greece

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Horticulture, 2020
Response of tritordeum, ‘Bulel’ variety, on organic and inorganic fertilization was observed through a field experiment in Greece. So as to evaluate, a field experiment was set up in Randomized Complete Block Design (RCBD) where blocks were four ...
Antigolena FOLINA, Ioanna KAKABOUKI, Efpraxia KONTONASAKI, Stella KARYDOGIANNI, Dimitrios VOSKOPOULOS, Dimitrios F. BESLEMES, Dimitrios BILALIS   +6 more
doaj   +1 more source

Study of Influence of Calcium Content in Milk on Quality Indicators of Cottage Cheese [PDF]

, 2017
The analysis was realized, and the dependence between the calcium content and organoleptic and functional-technological properties of milk as a raw material for producing sour milk cheese was determined.
Grynchenko, N. (Nataliya), Pyvovarov, P. (Pavlo), Tyutyukova, D. (Daria)   +2 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Alteration in the Expression of Cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the Liver of Mouse Induced by Microcystin-LR

Toxins, 2015
Microcystins (MCs) are cyclic heptapeptide toxins and can accumulate in the liver. Cytochrome P450s (CYPs) play an important role in the biotransformation of endogenous substances and xenobiotics in animals.
Bangjun Zhang, Yang Liu, Xiaoyu Li
doaj   +1 more source

Draft genome sequence of Frankia sp. strain DC12, an atypical, noninfective, ineffective isolate from Datisca cannabina [PDF]

, 2015
Frankia sp. strain DC12, isolated from root nodules of Datisca cannabina, is a member of the fourth lineage of Frankia, which is unable to reinfect actinorhizal plants.
Beauchemin, Nicholas, Cantor, Michael N., Copeland, Alex, Furnholm, Teal, Ghodhbane-Gtari, Faten, Goodwin, Lynne, Gtari, Maher, Huntemann, Marcel, Ivanova, Natalia, Kyrpides, Nikos, Markowitz, Victor, Mavrommatis, Kostas, Mikhailova, Natalia, Nouioui, Imen, Oshone, Rediet, Ovchinnikova, Galina, Pagani, Ioanna, Palaniappan, Krishnaveni, Pati, Amrita, Sen, Arnab, Shapiro, Nicole, Szeto, Ernest, Tisa, Louis S., Wall, Luis, Wishart, Jessie, Woyke, Tanja   +25 more
core   +3 more sources