Results 191 to 200 of about 54,964 (292)

Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley   +1 more source

Decoding Protein Corona Through Synchrotron-Based Small-Angle X‑Ray Scattering. [PDF]

ACS Omega
Carvalho JTT, Malfatti-Gasperini A, Boyd BJ, Wang L, Cardoso MB.   +4 more
europepmc   +1 more source

Lipid adsorbed on the surface of nanomaterials enhances protein corona formation.

Environ Sci Nano
Heckman MM, Cai CS, Kalpattu A, Simmons EM, Tighe RM, Payne CK.   +5 more
europepmc   +1 more source

PEGylation-Driven Remodeling of the Protein Corona on PLGA Nanoparticles: Implications for Macrophage Recognition. [PDF]

Biomacromolecules
Spinelli L, D'Anna P, Morretta E, Cassiano C, Piccolo V, De Rosa M, Amico R, De Cicco P, Brancaccio D, Conte C, Zampella A, Quaglia F, Monti MC.   +12 more
europepmc   +1 more source

The Challenges and Opportunities of Protein Coronas for Nanoscale Biomolecular Sensing [PDF]

Samuel Cheeseman, Parisa Moazzam, Negar Mahmoudi, Morteza Mahmoudi, Frank Caruso, Antonio Tricoli, David R. Nisbet   +6 more
openalex   +1 more source

A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats

Animal Models and Experimental Medicine, EarlyView.
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies, Vitaris Kodogo, Johannes Frederik Wentzel, Francis Edwin Smit   +3 more
wiley   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Multiplexed Nanoparticle Protein Corona Enables Accurate and Precise Deep Plasma Proteomics. [PDF]

J Proteome Res
Huang T, Wang J, Stukalov A, Kreimer S, Zhao X, Cantrell LS, Zhou X, Brewer A, Ho G, Murolo F, Quach K, Figa M, Just S, Castro G, Elgierari E, Benz RW, Motamedchaboki K, Batzoglou S, Farokhzad OC, Van Eyk JE, Siddiqui A.   +20 more
europepmc   +1 more source

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source

Engineered protein corona sustains stealth functionality of nanocarriers in plasma. [PDF]

J Nanobiotechnology
Zhang X, Si S, Lieberwirth I, Landfester K, Mailänder V.   +4 more
europepmc   +1 more source