Results 121 to 130 of about 103,093 (251)

Protein crystallography [PDF]

, 2011
openaire   +4 more sources

Compact tape‐driven sample delivery system for serial femtosecond crystallography

Journal of Applied Crystallography, EarlyView.
A tape‐driven liquid sample droplet delivery system for serial femtosecond crystallography is described.We have developed a compact tape drive (CoT) with on‐demand sample delivery for time‐resolved serial femtosecond crystallography (SFX) experiments, which can deliver sample droplets and/or initiate reactions with a drop‐on‐drop strategy.
Jungmin Kang, Yoshiaki Shimazu, Fangjia Luo, Ayumi Yamashita, Tomoyuki Tanaka, Yuichi Inubushi, Kensuke Tono, Nipawan Nuemket, Allen M. Orville, So Iwata, Eriko Nango, Makina Yabashi   +11 more
wiley   +1 more source

Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography. [PDF]

J Appl Crystallogr, 2019
Helliwell JR, Minor W, Weiss MS, Garman EF, Read RJ, Newman J, van Raaij MJ, Hajdu J, Baker EN.   +8 more
europepmc   +4 more sources

Structure and composition of supported lipid bilayers: a comparison between solvent‐assisted lipid bilayer and vesicle fusion methods

Journal of Applied Crystallography, EarlyView.
Neutron reflectometry is used to compare supported lipid bilayers formed by vesicle fusion and solvent‐assisted lipid bilayer (SALB) methods, revealing structurally comparable architectures with minor differences in acyl chain thickness and low residual solvent incorporation.
Birgit Felderer, Claire Buchanan, Shuhong Wang, Hsin-Hui Shen, Andrew Nelson, Stephen C. L. Hall, Marité Cárdenas   +6 more
wiley   +1 more source

Neutron reflectometry instrumentation at the ISIS source: current state

Journal of Applied Crystallography, EarlyView.
This article presents the current capabilities of the four time‐of‐flight neutron reflectometers at the ISIS Neutron and Muon Source, highlighting recent advances in instrumentation, automation and data analysis that enable high‐precision studies of interfacial structures across diverse scientific fields.Neutron reflectometry (NR) at the ISIS Neutron ...
Mario Campana, Andrew Caruana, Luke Clifton, Stephen Hall, Arwel Hughes, Christy Kinane, Maximilian Skoda, Oleksandr Tomchuk, John Webster   +8 more
wiley   +1 more source

Crystal structure of carbon–nitrogen hydrolase from Helicobacter pylori G27

Acta Crystallographica Section F, EarlyView.
H. pylori carbon–nitrogen hydrolase was produced and crystallized, and its 2.1 Å resolution structure is reported.Carbon–nitrogen hydrolases (CNHs) are members of the diverse nitrilase superfamily of enzymes that facilitate cellular adaptation to environmental stress by metabolizing nitrogen, detoxifying xenobiotics and catabolizing environmentally ...
Aruesha Srivastava, Jesuferanmi P. Ayanlade, Lema Suleiman, Hannah Udell, Jan Abendroth, Donald J. Lorimer, Thomas E. Edwards, Bart L. Staker, Rachael Zigweid, Sandhya Subramanian, Peter J. Myler, Graham Chakafana, Oluwatoyin A. Asojo   +12 more
wiley   +1 more source

Critical evaluation of three cryo‐EM structures of particulate methane monooxygenase by quantum refinement

Acta Crystallographica Section D, EarlyView.
We have studied the copper sites in three cryogenic electron‐microscopy structures of particulate methane monooxygenase with quantum refinement. We show that the CuA, CuC and CuD sites are correctly modelled and that the CuB site is mononuclear in all structures, whereas we find no support for copper in the suggested trinuclear active site or two sites
Gayathri Yuvaraj, Kristoffer J. M. Lundgren, Elija Veenman, Esko Oksanen, Ulf Ryde   +4 more
wiley   +1 more source

Application of differential scanning fluorimetry to X-ray protein crystallography. [PDF]

IUCrJ
Sato Y, Senda T.
europepmc   +1 more source

Serial protein crystallography in an electron microscope. [PDF]

Nat Commun, 2020
Bücker R, Hogan-Lamarre P, Mehrabi P, Schulz EC, Bultema LA, Gevorkov Y, Brehm W, Yefanov O, Oberthür D, Kassier GH, Dwayne Miller RJ.   +10 more
europepmc   +1 more source

Crystallographic fragment screening against SARS‐CoV‐2 nonstructural protein 1 using the F2X‐Entry Screen and a newly developed fragment library

Acta Crystallographica Section D, EarlyView.
Two crystallographic fragment screening campaigns against SARS‐CoV‐2 nonstructural protein 1 resulted in the identification of 21 new hits.Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) continues to threaten global health. This underpins the need for novel therapeutics against this virus.
Frank Lennartz, Jan Wollenhaupt, Melanie Oelker, Paula Fröling, Uwe Mueller, Anke Deckers, Christoph Grathwol, Stefan Bräse, Nicole Jung, Manfred S. Weiss   +9 more
wiley   +1 more source