Results 311 to 320 of about 8,887,267 (401)

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

SUMO2 inhibits ACSL3 protein degradation to antagonize erastin-induced ferroptosis in hepatocellular carcinoma. [PDF]

Discov Oncol
Shen Y, Ye B, Li C.
europepmc   +1 more source

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

Advanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila, Anh Ha, Morgan R. Chandler, Nathalia Leal Santos, Taejin Kim, Hannah S. Newton, Marina A. Dobrovolskaia, Kirill A. Afonin   +7 more
wiley   +1 more source

PROTAC-induced protein structural dynamics in targeted protein degradation. [PDF]

Elife
Wu KY, Hung TI, Chang CA.
europepmc   +1 more source

Customizable Aptamer-Engineered Nano-Lysosome-Targeting Chimeras Enable Receptor-Independent and High-Fidelity Degradation of Membrane Protein

Ran Liu, Yangfang Yun, Zhiyuan Feng, Zhe Chuan Feng, Wenxian Zhang, Y. Ye, Jingjing Zhang   +6 more
openalex   +1 more source

Calcium Imparts Advanced Functionalities to Silk Hydrogels for Biofabrication and Biomedical Innovation

Advanced Functional Materials, EarlyView.
The addition of calcium ions to silk fibroin enhances the hydrogel properties and, when combined with visible light crosslinking, enables compatibility with advanced light‐based fabrication techniques. Calcium ions extend the shelf‐life of silk and facilitate the fabrication of multizonal, multilayered constructs for advanced stimuli‐responsive ...
Hien A. Tran, Anton Maraldo, Chi Cong Nguyen, Trinh Thi‐Phuong Ho, Lauryn Srethbhakdi, Habib Joukhdar, Quinn van Hilst, Syamak Farajikhah, Fariba Dehghani, Thanh Nho Do, Khoon S. Lim, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Rapid protein degradation systems to determine gene function in vivo. [PDF]

Lab Anim (NY)
Scott TG, Guertin MJ.
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Protein degradation of antizyme depends on the N-terminal degrons. [PDF]

Protein Sci
Hsieh JY, Leong PY, Yang YF, Liu YL, Liu GY, Hung HC.   +5 more
europepmc   +1 more source

Four Dairy Products Mitigates Sarcopenia in Mice by Modulating Muscle Inflammation, Autophagy, and Protein Degradation. [PDF]

Food Sci Nutr
Sun M, Wu T, Wang R, Ma Y, Han Y, Hou Y, Zhang Z.   +6 more
europepmc   +1 more source