Results 61 to 70 of about 16,987,595 (305)
Folding and aggregation of designed proteins [PDF]
Proceedings of the National Academy of Sciences, 1998 Protein aggregation is studied by following the simultaneous folding of two designed identical 20-letter amino acid chains within the framework of a lattice model and using Monte Carlo simulations. It is found that protein aggregation is determined by elementary structures (partially folded intermediates) controlled by local contacts among some of the ...
Broglia R. A. +4 more
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An artificial immune system for clustering amino acids in the context of protein function classification [PDF]
, 2009 This paper addresses the classification task of data mining (a form of supervised learning) in the context of an important bioinformatics problem, namely the prediction of protein functions.
Timmis, Jon +5 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga +3 more
wiley +1 more source
Protein Evolution and Design [PDF]
Annual Review of Biochemistry, 2018 This article introduces the Protein Evolution and Design theme of the Annual Review of Biochemistry Volume 87.
openaire +2 more sources
Exploration of the Determinants of Protein Structure and Stability by Protein Design [PDF]
, 2005 Optimization of Rotamers by Iterative Techniques (ORBIT) has been used to calculate novel sequences for several small proteins. A partial sequence design (20 of 28 residues) is described for the zinc finger Zif268 (beta-beta-alpha) motif.
Sarisky, Catherine Ann
core +1 more source
Plant Communications, 2020 Cytochrome P450s (P450s) are the most versatile catalysts and are widely used by plants to synthesize a vast array of structurally diverse specialized metabolites that not only play essential ecological roles but also constitute a valuable resource for ...
Yi Shang, Sanwen Huang
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Design and folding of dimeric proteins [PDF]
Proteins: Structure, Function, and Bioinformatics, 2002 Abstract In a similar way in which the folding of single‐domain proteins provides an important test in the study of self‐organization, the folding of homodimers constitutes a basic challenge in the quest for the mechanisms that are the basis of biological recognition. Dimerization is studied by following the evolution of two identical
Tiana, G., Broglia, R. A.
openaire +3 more sources
Different Approaches For Protein Engineering In Industrial Biotechnology [PDF]
, 2011 Protein engineering is the novel field which has wide applications from pharmaceutics, industry, commercial, laundry and research. It may apply rational design or non rational design or both.
Muhammad Waheed Akhtar, Israr Khan
core
Introducing Experience Goals into Packaging Design [PDF]
, 2016 Consumer experiences are an increasingly important driving force for commerce, affecting also packaging design. Yet, experience design for packages is rarely studied.
Roto, Virpi +3 more
core +1 more source