Structural, functional and proteomic changes of proteins during rice yellowing [PDF]
High temperature storage (40 °C, 60 % relative humidity, 6 months) induces rice yellowing and affects protein properties. Physiochemical analysis revealed increased disulfide bonds, particle size, and surface hydrophobicity in yellowed rice protein ...
Yuqian Liu +9 more
doaj +2 more sources
Isoquercetin and Zafirlukast Cooperatively Suppress Tumor Growth and Thromboinflammatory Signaling in a Xenograft Model of Ovarian Cancer. [PDF]
Treatment using either the thiol isomerase inhibitor isoquercetin or zafirlukast lowers tissue factor levels, decreases VEGF, inhibits PD‐L1, and TMEM176B in a xenograft model of ovarian cancer. A combination of the two agents, at threefold lower concentrations than either drug, significantly enhanced the inhibition further, suggesting a dual action of
Keovilay JA +4 more
europepmc +2 more sources
Meloidogyne graminicola protein disulfide isomerase may be a nematode effector and is involved in protection against oxidative damage [PDF]
The rice root-knot nematode, Meloidogyne graminicola, is a serious pest in most rice-growing countries. Usually, nematodes employ antioxidants to counteract the harm of reactive oxygen species (ROS) and facilitate their infection.
Zhong-ling Tian +4 more
doaj +2 more sources
Atypical thioredoxin Patrx2 enhances alginate production in mucoid Pseudomonas aeruginosa [PDF]
Pseudomonas aeruginosa, an opportunistic human pathogen, is known for its ability to respond and adapt to its environment, employing intricate adaptation mechanisms that can lead to the formation of complex biofilms.
Marie M. Grandjean +7 more
doaj +2 more sources
The leader of the capsid protein from Feline calicivirus must be palmitoylated and form oligomers through disulfide bonds for efficient viral replication [PDF]
Feline calicivirus (FCV), a member of the genus Vesivirus and a model for studying members of the family Caliciviridae, has been used to understand the biology and viral replication of etiological agents of medical and veterinary importance.
Yoatzin Peñaflor-Téllez +7 more
doaj +2 more sources
A Global Identification of Protein Disulfide Isomerases from 'duli' Pear (Pyrus betulaefolia) and Their Expression Profiles under Salt Stress. [PDF]
Zhang H +10 more
europepmc +3 more sources
Downregulated miR-181a alleviates H2O2-induced oxidative stress and cellular senescence by targeting PDIA6 in human foreskin fibroblasts [PDF]
Background Oxidative stress is strongly associated with cellular senescence. Numerous studies have indicated that microRNAs (miRNAs) play a critical part in cellular senescence.
Yan Huang +5 more
doaj +1 more source
Protein disulfide isomerases as potential therapeutic targets for influenza A and B viruses. [PDF]
Kim Y, Chang KO.
europepmc +3 more sources
Switchgrass rust caused by Puccinia novopanici (P. novopanici) has the ability to significantly affect the biomass yield of switchgrass, an important biofuel crop in the United States. A comparative genome analysis of P.
Raja Sekhar Nandety +6 more
doaj +1 more source
PDI-Regulated Disulfide Bond Formation in Protein Folding and Biomolecular Assembly
Disulfide bonds play a pivotal role in maintaining the natural structures of proteins to ensure their performance of normal biological functions. Moreover, biological molecular assembly, such as the gluten network, is also largely dependent on the ...
Jiahui Fu +3 more
doaj +1 more source

