Results 271 to 280 of about 7,816,364 (345)

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

Advanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou, Zhihang Zhou, Houyu Ju, Chaoyang Guo, Fangxing Zhu, Yiyi Zhang, Xu Chen, Tongchao Zhao, Laiping Zhong, Jingzhou Hu   +9 more
wiley   +1 more source

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

Advanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang, Jingrui Wang, Qiaowan Chen, Chen Jiao, Yun Chen, Zhongshou Wu, Zhonghua Ma   +6 more
wiley   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

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Protein Electrophoresis and Immunofixation

Clinical Chemistry, Immunology and Laboratory Quality Control, 2014
Protein electrophoresis is a widely used screening test for monoclonal gammopathies. Again, multiple methodologies are in practice. This chapter will deal with serum protein electrophoresis by conventional gel methods as well as capillary electrophoresis.
Amitava Dasgupta, Amer Wahed
openaire   +2 more sources

Introduction to Protein Electrophoresis

Methods in molecular biology, 2012
This chapter discusses, briefly, the developments in electrophoresis of proteins from Tiselius' moving boundary electrophoresis to the modern day two-dimensional polyacrylamide gel electrophoresis. It also touches upon the staining methods used to visualize total proteins postelectrophoresis.
P. Srinivas
openaire   +4 more sources

Difference gel electrophoresis. A single gel method for detecting changes in protein extracts

Electrophoresis, 1997
Mustafa Ünlü, Mary E. Morgan, J. Minden   +2 more
semanticscholar   +3 more sources

Protein electrophoresis

Current Opinion in Biotechnology, 1993
Many significant advances have occurred recently in the field of protein electrophoresis and related technologies. Improvements have been made in capillary electrophoresis in apparatus design, detection, and capillary modification with coatings and fillers.
T E, Zewert, M G, Harrington
openaire   +4 more sources

Serum and Urine Protein Electrophoresis and Serum-Free Light Chain Assays in the Diagnosis and Monitoring of Monoclonal Gammopathies.

The Journal of Applied Laboratory Medicine, 2020
BACKGROUND Laboratory methods for diagnosis and monitoring of monoclonal gammopathies have evolved to include serum and urine protein electrophoresis, immunofixation electrophoresis, capillary zone electrophoresis, and immunosubtraction, serum-free light
Gurmukh Singh
semanticscholar   +1 more source

Electrophoresis of Proteins

CRC Critical Reviews in Clinical Laboratory Sciences, 1970
(1970). Electrophoresis of Proteins. CRC Critical Reviews in Clinical Laboratory Sciences: Vol. 1, No. 2, pp. 233-245.
Lena A. Lewis, Miriam Reiner
openaire   +2 more sources

Countercurrent Electrophoresis of Proteins

Nature, 1967
COUNTERCURRENT distribution has been successfully applied to the separation of proteins and similar large molecules in certain water–organic solvent systems1 and in some two-phase water systems containing hydrophilic polymers2. These systems have not been widely used, presumably because they depend on specific solvent systems which are not easy to find.
J, Broome, S, Raymond
openaire   +2 more sources