Results 91 to 100 of about 8,702,941 (302)
Immunological Compatibility Status of Placenta-Derived Stem Cells is Mediated by Scaffold 3D Structure [PDF]
, 2018 Placenta-derived amniotic epithelial cells (AECs), a great cell source for tissue engineering and stem cell therapy, are immunologically inert in their native state; however, immunological changes in these cells after culture and differentiation have ...
Azizian, Sara +8 more
core +2 more sources
Molecular Oncology, 2020 Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death.
Marta Pozniak +9 more
doaj +1 more source
Engineering Nutritious Proteins [PDF]
Biotechnology and Genetic Engineering Reviews, 1997 (1997). Engineering Nutritious Proteins. Biotechnology and Genetic Engineering Reviews: Vol. 14, No. 1, pp. 191-210.
openaire +3 more sources
De novo design of bioactive protein switches. [PDF]
, 2019 Allosteric regulation of protein function is widespread in biology, but is challenging for de novo protein design as it requires the explicit design of multiple states with comparable free energies. Here we explore the possibility of designing switchable
Baker, David +14 more
core
Structural and dynamic changes associated with beneficial engineered single-amino-acid deletion mutations in enhanced green fluorescent protein. [PDF]
, 2014 Single-amino-acid deletions are a common part of the natural evolutionary landscape but are rarely sampled during protein engineering owing to limited and prejudiced molecular understanding of mutations that shorten the protein backbone.
Arpino, JA, Jones, DD, Rizkallah, PJ
core +2 more sources
Adaptive machine learning for protein engineering [PDF]
Current Opinion in Structural Biology, 2021 B. Hie, Kevin Kaichuang Yang
semanticscholar +1 more source
Human acid sphingomyelinase structures provide insight to molecular basis of Niemann–Pick disease
Nature Communications, 2016 Genetic alterations in the protein acid sphingomyelinase (ASM) lead to ASM deficiency and have been associated with Niemann–Pick disease. Here, the authors report the crystal structures of ASM alone and bound to its product, and discuss the catalytic ...
Yan-Feng Zhou +5 more
doaj +1 more source
Evolution of sparsity and modularity in a model of protein allostery
, 2014 The sequence of a protein is not only constrained by its physical and biochemical properties under current selection, but also by features of its past evolutionary history.
Hemery, Mathieu, Rivoire, Olivier
core +3 more sources
Frontiers in Microbiology, 2018 Oxidoreductases are ubiquitous enzymes that catalyze an extensive range of chemical reactions with great specificity, efficiency, and selectivity. Most oxidoreductases are nicotinamide cofactor-dependent enzymes with a strong preference for NADP or NAD ...
A. Chánique, Loreto P. Parra
semanticscholar +1 more source
Automatic Extraction of Protein Interaction in Literature [PDF]
arXiv, 2014 Protein-protein interaction extraction is the key precondition of the construction of protein knowledge network, and it is very important for the research in the biomedicine. This paper extracted directional protein-protein interaction from the biological text, using the SVM-based method. Experiments were evaluated on the LLL05 corpus with good results.
arxiv