Results 161 to 170 of about 677,670 (306)

Engineering a Proximity-Directed O-GlcNAc Transferase for Selective Protein O-GlcNAcylation in Cells

, 2020
Daniel H. Ramirez, Chanat Aonbangkhen, Hung‐Yi Wu, Jeffrey A. Naftaly, Stephanie Tang, Timothy R. O’Meara, Christina M. Woo   +6 more
openalex   +2 more sources

Engineering of Acid Insensitive Proteins [PDF]

, 2011
P.C. Bell-Upp, A.C. Robinson, Erika L. Wheeler, Bertrand García‐Moreno   +3 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Protein engineering for strain engineering

New Biotechnology, 2014
Ping Zheng, Jibin Sun
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Protein Engineering of Biosynthetic Enzymes Unlocks Libraries of Bioactive Tilimycin Analogs. [PDF]

ACS Catal
MacDonald MR, Hasselbeck J, Gulick AM.
europepmc   +1 more source

Computational Reverse Protein Engineering of a Lipase from Pseudomonas Aeruginosa in N -Hexane

Myrnel Diche Almoradie-Fortuna, Jaidriel Meg G. Cabanding, Steve S.‐F. Yu, Zhi‐Han Lin, Adam Jo J. Elatico, Ricky B. Nellas   +5 more
openalex   +1 more source

Engineering Allostery into Proteins

, 2019
Scott D. Gorman, Rebecca N. D’Amico, Dennis S. Winston, David D. Boehr   +3 more
openalex   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Improving split-HaloTag through computational protein engineering. [PDF]

Protein Sci
Wilhelm J, Nickel L, Lin YH, Hiblot J, Johnsson K.   +4 more
europepmc   +1 more source