Results 291 to 300 of about 8,703,040 (401)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Construction of the Thermostable D-Allulose 3-Epimerase from Arthrobacter globiformis M30 by Protein Engineering Method. [PDF]

J Appl Glycosci (1999)
Ohtani K, Shimada K, Gullapalli PK, Ishikawa K.   +3 more
europepmc   +1 more source

Interatomic potentials and solvation parameters from protein engineering data for buried residues [PDF]

, 2002
Andrei L. Lomize, Mikhail Reibarkh, Irina D. Pogozheva   +2 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

New advances in protein engineering for industrial applications: Key takeaways. [PDF]

Open Life Sci
Ndochinwa GO, Wang QY, Okoro NO, Amadi OC, Nwagu TN, Nnamchi CI, Moneke AN, Odiba AS.   +7 more
europepmc   +1 more source

Genetic engineering of Streptococcus gordonii for the simultaneous display of two heterologous proteins at the bacterial surface [PDF]

, 2002
Tiziana Maggi
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Improving Downstream Process Related Manufacturability Based on Protein Engineering-A Feasibility Study. [PDF]

Eng Life Sci
Capito F, Wong TH, Faust C, Brand K, Dittrich W, Sommerfeld M, Tiwari G, Langer T.   +7 more
europepmc   +1 more source

Engineering green fluorescent protein to a redox switch [PDF]

, 2002
A. Henriksen, H. Oestergaard, Flemming Hansen, Jakob R. Winther   +3 more
openalex   +1 more source

Integrating protein engineering with process design for biocatalysis

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2018
J. Woodley
semanticscholar   +1 more source