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The structure of protein evolution and the evolution of protein structure
Current Opinion in Structural Biology, 2008The observed distribution of protein structures can give us important clues about the underlying evolutionary process, imposing important constraints on possible models. The availability of results from an increasing number of genome projects has made the development of these models an active area of research.
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Exons and the evolution of proteins
Trends in Biochemical Sciences, 1983Publisher Summary This chapter discusses exons and evolution of proteins. The splitting of most eukaryotic structural genes into coding sequences (exons) and noncoding sequences (introns) is widely interpreted in terms of evolutionary processes concerned with the gene products.
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Systems Biology in Reproductive Medicine, 2018
Antifreeze proteins (AFPs) protect marine fishes from freezing in icy seawater. They evolved relatively recently, most likely in response to the formation of sea ice and Cenozoic glaciations that occurred less than 50 million years ago, following a greenhouse Earth event.
Peter L, Davies, Laurie A, Graham
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Antifreeze proteins (AFPs) protect marine fishes from freezing in icy seawater. They evolved relatively recently, most likely in response to the formation of sea ice and Cenozoic glaciations that occurred less than 50 million years ago, following a greenhouse Earth event.
Peter L, Davies, Laurie A, Graham
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Protein evolution in cyanobacteria
Nature, 1976THERE has been a great deal written in recent years on evolutionary relationships between prokaryotes and eukaryotes1,2, and the possible origin of photosynthesis in eukaryotic cells by endosymbiosis of a cyanobacterium2,3. Molecular methods have been used in an attempt to elucidate the principal events in Precambrian cellular evolution.
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Parsimony in protein evolution
Biophysical Chemistry, 2002Pohl found the activation enthalpy and entropy for melting of his mesophilic proteins to be linear in the total number of residues and Privalov and colleagues found this same linearity for the standard heat-capacity, enthalpy and entropy changes in the overall melting equilibria.
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2021
This chapter focuses on protein evolution, which proceeds through generation of variation by mutations in DNA—gene frequencies in populations can change either by selection of favourable variants, or non-selective drift. There are two components of protein evolution. The first is divergence of amino-acid sequences within domains.
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This chapter focuses on protein evolution, which proceeds through generation of variation by mutations in DNA—gene frequencies in populations can change either by selection of favourable variants, or non-selective drift. There are two components of protein evolution. The first is divergence of amino-acid sequences within domains.
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Character and evolution of protein–protein interfaces
Physical Biology, 2005Protein-protein interactions create the macromolecular assemblies and sequential signaling pathways essential for cell function. Their number far exceeds the number of proteins themselves and their experimental characterization, while improving, remains relatively slow.
Ivica, Res, Olivier, Lichtarge
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1992
Abstract The study of protein evolution, like that of morphological evolution, is a multi-level enterprise. At the most fundamental level are those studies that infer what actually happened. At the next level are studies of rates of change. Once we know what happened, we want to know how quickly it happened.
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Abstract The study of protein evolution, like that of morphological evolution, is a multi-level enterprise. At the most fundamental level are those studies that infer what actually happened. At the next level are studies of rates of change. Once we know what happened, we want to know how quickly it happened.
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