Results 201 to 210 of about 2,111,356 (267)

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, EarlyView.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

The oncogene protein kinase PIM1 regulates mammalian erythroblast enucleation. [PDF]

Commun Biol
Zhang H, Xu Y, Li Y, Zhang J, Xiao J, Wang C, Wang Y, An X, Zhang S.   +8 more
europepmc   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Obacunone Inhibits Microglia-Mediated Neuroinflammation and Ischemic Injury by Targeting Mitogen-Activated Protein Kinase 1. [PDF]

J Inflamm Res
Huang J, Hu Z, Zhang J, Xiao J, Zhang R, Xia S, Yang H, Bao X, Zhang F, Xu Y, Zhu X, Jin J.   +11 more
europepmc   +1 more source

Lipid Pocket Binders Impose Allosteric Changes of Protein Dynamics Around the Active Site of the Protein Kinase p38α. [PDF]

Angew Chem Int Ed Engl
Medina Gómez S, Homberg LT, Bührmann M, Rauh D, Linser R.   +4 more
europepmc   +1 more source

1,1-Diethoxyethane enhances aerobic respiration in human mitochondria via activation of AMP-activated protein kinase. [PDF]

Commun Biol
Nguyen Huu T, Duong Thanh H, Kim MK, Kumar Sah D, Trinh VH, Yoon HJ, Choi JM, Lee GH, Kim SY, Lee SR.   +9 more
europepmc   +1 more source

Mitogen-activated protein kinase (MAPK) gene family identification reveals GhMPK10-mediated regulation of abiotic stress tolerance through protein kinase signaling cascades in cotton. [PDF]

BMC Plant Biol
Li Y, Su R, Wang K, Wang J, Zhang D.
europepmc   +1 more source

Protein Kinase C Family: Structures, Biological Functions, Diseases, and Pharmaceutical Interventions. [PDF]

MedComm (2020)
Li Y, Jiang Y, Hu Z, Yang S, Li L, Xiong C, Gao Y, Sun W, Zhang Y.   +8 more
europepmc   +1 more source

Protein kinase A fuels positive feedback loops during Th1 cell differentiation. [PDF]

Proc Natl Acad Sci U S A
Zhu J.
europepmc   +1 more source