Results 191 to 200 of about 2,152,541 (363)

AtSnRK2.4 Functions as an ABA-Responsive Protein Kinase in Arabidopsis. [PDF]

Physiol Plant
Adamo M, Tournaire-Roux C, Rofidal V, Nacry P, Demolombe V, Crabos A, Maurel C, Santoni V.   +7 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Protein kinase A: a quirky prototype. [PDF]

FEBS J
Gold MG.
europepmc   +1 more source

Affinity labeling of catalytic subunit of bovine heart muscle cyclic AMP-dependent protein kinase by 5'-p-fluorosulfonylbenzoyladenosine.

, 1979
C.S. Hixson, E G Krebs
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Identification of viral activators of the HSV-2 UL13 protein kinase. [PDF]

J Virol
Koyanagi N, Takeshima K, Shio S, Maruzuru Y, Kato A, Kawaguchi Y.   +5 more
europepmc   +1 more source

Positive cooperativity in guanosine 3':5'-monophosphate binding to guanosine 3':5'-monophosphate-dependent protein kinase.

, 1979
R. W. McCUNE, Gordon N. Gill
openalex   +1 more source

Regulation of protein synthesis: Activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2 [PDF]

, 1978
Daniel H. Levin, Irving M. London
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The oncogene protein kinase PIM1 regulates mammalian erythroblast enucleation. [PDF]

Commun Biol
Zhang H, Xu Y, Li Y, Zhang J, Xiao J, Wang C, Wang Y, An X, Zhang S.   +8 more
europepmc   +1 more source