Results 211 to 220 of about 2,670,458 (365)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

NEK8, a NIMA-family protein kinase at the core of the ciliary INV complex. [PDF]

Cell Commun Signal
Roig J.
europepmc   +1 more source

Dynamics connect substrate recognition to catalysis in protein kinase A.

Nature Chemical Biology, 2010
L. Masterson, Cecilia Y. Cheng, Tao Yu, M. Tonelli, A. Kornev, Susan S. Taylor, G. Veglia   +6 more
semanticscholar   +1 more source

Protein Kinase Modulator from Lobster Tail Muscle

, 1973
Thomas E. Donnelly, J.F. Kuo, Procerfina L. Reyes, Yung-Pin Liu, Paul Greengard   +4 more
openalex   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

PI3Kβ moonlights as a protein kinase: driving fatty acid metabolism and histone acetylation in cancer. [PDF]

Cancer Biol Med
Duan Y, Liu J, Xu J, Fang J.
europepmc   +1 more source

Characterization of Protein Kinases from Rabbit Reticulocytes

, 1974
Jolinda A. Traugh, Robert R. Traut
openalex   +1 more source

Inhibition by diuretics of cyclic 3′,5′‐AMP‐dependent protein kinase from toad bladder epithelium [PDF]

, 1973
D. R. Ferguson, B. R. Twite
openalex   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Anti-Cryptosporidium efficacy of BKI-1708, an inhibitor of Cryptosporidium calcium-dependent protein kinase 1. [PDF]

PLoS Negl Trop Dis
Choi R, Hulverson MA, Schaefer DA, Betzer DP, Riggs MW, Huang W, Sun V, Whitman GR, McCloskey MC, Marsh K, Buck WR, Wagner DS, Yang J, Bowman AP, Ciurlionis R, Ajiboye J, Hemphill A, Sigalapalli DK, Arnold SLM, Barrett LK, Ojo KK, Fan E, Van Voorhis WC.   +22 more
europepmc   +1 more source