Ribosome‐associated protein kinase from Saccharomyces cerevisiae [PDF]
Nikodem Grankowski+2 more
openalex +1 more source
Mitochondrial DNA disorders in neuromuscular diseases in diverse populations
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao+34 more
wiley +1 more source
The Role of the Mitogen-Activated Protein Kinase Pathway in the Development of Laser-Induced Choroidal Neovascularization. [PDF]
Jang SY+11 more
europepmc +1 more source
Stimulation of uterine nonhistone protein phosphorylation and nuclear protein kinase activity by estradiol-17β [PDF]
Michael E. Cohen, Lewis J. Kleinsmith
openalex +1 more source
Calcium modulating ligand confers risk for Parkinson's disease and impacts lysosomes
Abstract Objective Several genetic loci known to confer risk for Parkinson's disease (PD) function in lysosomal pathways. We systematically screened common variants linked to PD risk by genome‐wide association studies (GWAS) for impact on cerebrospinal fluid (CSF) proteins reflecting lysosomal function.
Hanwen Zhang+16 more
wiley +1 more source
Tracking protein kinase targeting advances: integrating QSAR into machine learning for kinase-targeted drug discovery. [PDF]
Shahin R, Jaafreh S, Azzam Y.
europepmc +1 more source
Temperature Sensitivity of Cyclic-Adenosine-3':5'-Monophosphate-Binding Proteins, Activity of Protein Kinases and the Regulation of Cell Growth [PDF]
Rabi Simantov, Leo Sachs
openalex +1 more source
Skin calcium deposits in primary familial brain calcification: A novel potential biomarker
Abstract Objective Primary Familial Brain Calcification (PFBC) is a rare neurodegenerative disorder characterized by small vessel calcifications in the basal ganglia. PFBC is caused by pathogenic variants in different genes and its physiopathology is still largely unknown. Skin vascular calcifications have been detected in single PFBC cases, suggesting
Aron Emmi+8 more
wiley +1 more source