Results 261 to 270 of about 2,152,541 (363)

Inhibition of protein kinase R suppresses HIV replication and integration in CD4 T cells. [PDF]

J Virus Erad
Pyburn J, Zhao J, Wang L, Schank M, Hill AC, Banik P, Zhang Y, Wu XY, Lightner JW, Orfield HK, Leshaodo TO, El Gazzar M, Ning S, Moorman JP, Yao ZQ.   +14 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Protein Kinase CK2 Inhibition Represents a Pharmacological Chance for the Treatment of Skin Diseases. [PDF]

Int J Mol Sci
Scuruchi M, Speranza D, Bruschetta G, Vaccaro F, Galeano M, Pallio G, Vaccaro M, Borgia F, Li Pomi F, Collino M, Irrera N.   +10 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Phosphoglycerate dehydrogenase stabilizes protein kinase C delta type mRNA to promote hepatocellular carcinoma progression. [PDF]

Signal Transduct Target Ther
Cheng B, Peng P, Chen S, Liu R, Li X, Wang K, Ma J, Wang K, Tang N, Huang A.   +9 more
europepmc   +1 more source

Characteristics of Extracts from Interferon-treated HeLa Cells: Presence of a Protein Kinase and Endoribonuclease Activated by Double-stranded RNA and of an Inhibitor of mRNA Methylation

, 1977
S Shaila, Bernard Lebleu, G. E. Brown, Ganes C. Sen, Péter Lengyel   +4 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Correction to: Critical role of the SPAK protein kinase CCT domain in controlling blood pressure. [PDF]

Hum Mol Genet
europepmc   +1 more source

Protein kinase A is a dependent factor and therapeutic target in mouse models of fibrous dysplasia. [PDF]

Nat Commun
Liu Z, Xing L, Huang W, Ji N, Zhao H, Chen Q, Han X, Bai D, Zhao X.   +8 more
europepmc   +1 more source

Protein kinase inhibitor in sertoli cell-enriched rat testis. Specific regulation by follicle-stimulating hormone.

, 1979
Joseph S. Tash, John Dedman, Anthony R. Means   +2 more
openalex   +1 more source