Results 61 to 70 of about 1,326,529 (167)

Centrosomal actin pool levels regulated by localized PKA set the threshold for T cell polarization

open access: yesEMBO Reports
T lymphocyte migration triggered by chemokine stimulation is preceded by cell polarization. The acquisition of this asymmetry requires a profound cell rearrangement, particularly of the cytoskeleton.
Morgane Simao   +2 more
doaj   +1 more source

A versatile kinase mobility shift assay (KiMSA) for PKA analysis and cyclic AMP detection in sperm physiology (and beyond)

open access: yesFrontiers in Cell and Developmental Biology
The cAMP-dependent protein kinase (PKA) is one of the most extensively distributed kinases among intracellular signal cascades, with a pivotal role in the regulation of various processes, including the capacitation of sperm cells. Traditional assessments
Analia G. Novero   +7 more
doaj   +1 more source

PKA regulates autophagy through lipolysis during fasting

open access: yesMolecules and Cells
: Autophagy is a crucial intracellular degradation process that provides energy and supports nutrient deprivation adaptation. However, the mechanisms by which these cells detect lipid scarcity and regulate autophagy are poorly understood.
Yul Ji   +6 more
doaj   +1 more source

A Protein Kinase Cε/Protein Kinase D3 Signalling Axis Modulates RhoA Activity During Cytokinesis

open access: yesBiomedicines
Background: Protein kinase D3 (PKD3) is a member of the PKD family that has been implicated in many intracellular signalling pathways. However, defined statements regarding PKD isoform specificity and in vivo functions are rare.
Ursula Braun, Michael Leitges
doaj   +1 more source

Participation of cAMP in tacrine-induced gastric smooth muscle relaxation

open access: yesOpen Life Sciences, 2011
Prissadova Natalia   +4 more
doaj   +1 more source

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